Protein

MCA_05547_1

Length
641 amino acids

Gene name: SSA4D

Description: protein of the HSP70 family; has a role in SRP-dependent cotranslational protein-membrane targeting and translocation

Browser: contigD:1616879-1618805+

RNA-seq: read pairs 428, FPKM 8.2, percentile rank 22.8% (100% = highest expression)

Protein function

Annotation:SSA4Dprotein of the HSP70 family; has a role in SRP-dependent cotranslational protein-membrane targeting and translocation
KEGG:K03283HSPA1_8 heat shock 70kDa protein 1/8
EGGNOG:0PFQWHSP70heat shock
SGD closest match:S000000905SSA4Heat shock protein SSA4
CGD closest match:CAL0000184853SSA2Heat shock protein SSA2

Protein alignments

%idAln lengthE-value
MIA_05007_188.93%6140.0MIA_05007_1
Q6C0E9_YARLI86.70%6090.0YALI0F25289p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F25289g PE=3 SV=1
A0A0J9XDF4_GEOCN86.58%6110.0Similar to Saccharomyces cerevisiae YER103W SSA4 Heat shock protein that is highly induced upon stress OS=Geotrichum candidum GN=BN980_GECA10s02947g PE=3 SV=1
A0A060TFE3_BLAAD86.72%6100.0ARAD1D14740p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14740g PE=3 SV=1
A0A167C832_9ASCO86.56%6100.0Hsp70 family ATPase SSA3 OS=Sugiyamaella lignohabitans GN=SSA3 PE=3 SV=1
A0A1E3PCY5_9ASCO85.60%6110.0Heat shock protein 70 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44162 PE=3 SV=1
A0A1E4TGS8_9ASCO84.43%6100.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2600 PE=3 SV=1
HSP72_CANAL83.77%6160.0Heat shock protein SSA2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SSA2 PE=1 SV=4
UniRef50_P4658783.77%6160.0Heat shock protein SSA2 n=714 Tax=Eukaryota TaxID=2759 RepID=HSP72_CANAL
HSP74_YEAST83.11%6100.0Heat shock protein SSA4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSA4 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0457

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 641

Detailed signature matches

  1. Family IPR013126
    Heat shock protein 70 family
    1. PF00012 (HSP70)
    2. PR00301 (HEATSHOCK70)
  2. Domain IPR029047
    Heat shock protein 70kD, peptide-binding domain
    1. G3DSA:2.60.34.10
    2. SSF100920 (Heat sho...)
  3. Domain IPR029048
    Heat shock protein 70kD, C-terminal domain
    1. G3DSA:1.20.12...
    2. SSF100934 (Heat sho...)
  4. SITE IPR018181
    Heat shock protein 70, conserved site
    1. PS00297 (HSP70_1)
    2. PS01036 (HSP70_3)
    3. PS00329 (HSP70_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.42...
  3. SSF53067 (Actin-lik...)
  4. cd10233 (HSPA1-2_6-...)
  5. mobidb-lite (disord...)

Residue annotation

  1. nucleotide binding...
  2. NEF/HSP70 interact...
  3. BAG/HSP70 interact...
  4. SBD interface cd10...

Protein sequence

>MCA_05547_1
MSKAVGIDLGTTYSCVAHYTNDRVEIIANDQGDRTTPSYVSFNDTERLIGIAAKNQAAMNPKNTVFDAKRLIGRKFSDPE
VQNDMKHYPFKVIDKGGKPAIEVEFKGETKVFQPEEISSMVLTKMKETAENYLGTKVTDAVITVPAYFNDSQRQATKDAG
LIAGLNVLRIINEPTAAAIAYGLDKKSSGEKNVLIFDFGGGTFDVSLLTIEDGIFEVKATAGDTHLGGEDIDNKLVNFFI
QEFKRKNKKDISGNQRALRRLRTACERAKRTLSSSTQATIEIDSLYEGVDFYSSITRARFEELCGDIFRSTLEPVEKVLR
DAKIDKSQVNDIVLVGGSTRIPKIQKLVSDFFNGKEPSKSINPDEAVAYGAAVQAAILSGDTSNTKTEDLLLLDVAPLSL
GIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVYEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDID
ANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIERMVAEAEKYKEEDEKEAARIQAKNGLESYAYSLKNTISEANFKEK
VSEADREKLDKAIKETIDWLDNNQTATTEEFSDHQKELEGIANPIMTSFYGGAGVPPNMPGAGSSTSSAGGDSGPTVEEV
D

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.