Protein

MCA_05537_1

Length
959 amino acids

Gene name: CSE1

Description: Importin alpha re-exporter

Browser: contigD:1579905-1582962+

RNA-seq: read pairs 3448, FPKM 44.4, percentile rank 62.6% (100% = highest expression)

Protein function

Annotation:CSE1Importin alpha re-exporter
KEGG:K18423CSE1 exportin-2 (importin alpha re-exporter)
EGGNOG:0PFCMCSE1Chromosome segregation protein
SGD closest match:S000003207CSE1Importin alpha re-exporter
CGD closest match:CAL0000195471orf19.1229Importin-alpha export receptor

Protein alignments

%idAln lengthE-value
MIA_00901_156.45%9460.0MIA_00901_1
A0A060T952_BLAAD50.95%9460.0ARAD1D08844p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D08844g PE=4 SV=1
A0A1E3PNB3_9ASCO50.46%9710.0Cse1-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50624 PE=4 SV=1
UniRef50_A0A1E3PNB350.46%9710.0Cse1-domain-containing protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PNB3_9ASCO
A0A0J9X2G5_GEOCN48.66%9680.0Similar to Saccharomyces cerevisiae YGL238W CSE1 Nuclear envelope protein that mediates the nuclear export of importin alpha (Srp1p) OS=Geotrichum candidum GN=BN980_GECA01s01539g PE=4 SV=1
A0A167FAV5_9ASCO49.89%8780.0Cse1p OS=Sugiyamaella lignohabitans GN=CSE1 PE=4 SV=1
Q6C6Q8_YARLI45.94%9730.0YALI0E07139p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E07139g PE=4 SV=1
A0A1E4TIG2_9ASCO45.76%9440.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_71450 PE=4 SV=1
CSE1_YEAST44.78%9490.0Importin alpha re-exporter OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CSE1 PE=1 SV=2
A0A1D8PE78_CANAL41.05%10450.0Importin-alpha export receptor OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1229 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1971

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 959

Detailed signature matches

  1. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  2. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
  3. Domain IPR001494
    Importin-beta, N-terminal domain
    1. SM00913 (IBN_N_2)
    2. PS50166 (IMPORTIN_B_NT)
    3. PF03810 (IBN_N)
  4. Domain IPR013713
    Exportin/Importin, Cse1-like
    1. PF08506 (Cse1)
  5. Domain IPR005043
    CAS/CSE, C-terminal
    1. PF03378 (CAS_CSE1)

Protein sequence

>MCA_05537_1
MSNTTELANLFQQSLDHTRAKAVETTLKQQEQTPGFSVAVLNVVASNNVDSSSRLAAALYFKNLIKRRWRDQDGNMLLPD
EDMTKIKSAIIDFMTQLPPNLQVQIGEAVSIIADSDFPDRWMDLIPTLVSKLSEDPSSNNGVLTVAHSIFSRWRPLFRTD
QLFLEIKLALDQFAPTFLKLLQMIDTQIESHANDKKFLTEALKSMDLMMAIFYDFNCQDLPEFFEDNLNPLFEVVHKYLI
YKNPLFEDPDDDEAGPLEHLRTSICELLQLYTFRYEEVFAPLLPKFVETTWNLLTTTGPQSKYEILISKALSFLTYVAKV
PRHAQMFASEEALEQIIRNVILPNITLQESDEEMFEDDPIEFTRRDLEGSDSDTRRRAATDFLRELNNQNQNTVTQVVLK
YINEFLAAYKSNPEANWKQKDTAIYLFSAIAVKGTITNEGVTSVNEQVDIINFFTENIASDLTSTSGNPILVVDSIKYLY
VFRRQLTKDQFMVAFNYLDRHLEANEYVVYTYAAITIEKVLGIRSISDKNSYLFDKTDVSPMAEKWLSNLFKIISRQQTP
EKVAENEFLMKCILRILTCCKEACLPYAAVLLQQLVEIIKVISKNPSNPKFSHYTFESIGALIRYCASSLGASTIEPIIF
PTFLEILANDVSEFVPYTFQILAYLLEFYPSNQQLSENYTQLIRPLMSPALWELRGNVPSLTKLLQSILRHGSDIVVSSD
NLTPYLGIFQKLISMKFSETYGLDLLEDLFYNIKASDIAPYTNQIAVLLLQRLQTKTDKLVIRTASFIYSMAASTDKTGL
GPENVIQLFEKVQEGIFDRIFQLFLPATPKIVGIRNQRVALVGLTNLISKTTYYSTGTKNETIKLAVQALVQVLNSETML
KNPNEDINEDLETKTFDDEVSFGSSFSQLSIVSIPSVNPLSGVTNVKDYVFTGLRSIGSILQIALDEESKQALQKTGFA

GO term prediction

Biological Process

GO:0006886 intracellular protein transport

Molecular Function

GO:0005488 binding
GO:0005515 protein binding
GO:0008536 Ran GTPase binding

Cellular Component

None predicted.