Protein

MCA_05532_1

Length
360 amino acids

Gene name: FBA1

Description: Fructose-bisphosphate aldolase

Browser: contigD:1569767-1570850+

RNA-seq: read pairs 91332, FPKM 3126.0, percentile rank 98.6% (100% = highest expression)

Protein function

Annotation:FBA1Fructose-bisphosphate aldolase
KEGG:K01624FBA fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
EGGNOG:0PGPFFBA1fructose-bisphosphate aldolase
SGD closest match:S000001543FBA1Fructose-bisphosphate aldolase
CGD closest match:CAL0000186998FBA1Fructose-bisphosphate aldolase

Protein alignments

%idAln lengthE-value
MIA_00639_189.72%3600.0MIA_00639_1
A0A0J9X964_GEOCN84.44%3600.0Similar to Saccharomyces cerevisiae YKL060C FBA1 Fructose 1,6-bisphosphate aldolase OS=Geotrichum candidum GN=BN980_GECA05s05455g PE=4 SV=1
A0A060SX31_BLAAD83.29%3590.0ARAD1A01408p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A01408g PE=4 SV=1
A0A1E3PL56_9ASCO78.27%3590.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24459 PE=4 SV=1
Q6C4K5_YARLI76.37%3640.0YALI0E26004p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E26004g PE=4 SV=1
UniRef50_K1WTJ875.56%3601e-180Fructose-bisphosphate aldolase n=1 Tax=Marssonina brunnea f. sp. multigermtubi (strain MB_m1) TaxID=1072389 RepID=K1WTJ8_MARBU
A0A1E4THY1_9ASCO72.70%3597e-180Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_122941 PE=4 SV=1
ALF_YEAST70.56%3607e-175Fructose-bisphosphate aldolase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FBA1 PE=1 SV=3
ALF_CANAL73.06%3602e-173Fructose-bisphosphate aldolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FBA1 PE=1 SV=2
A0A170QXQ4_9ASCO79.41%2383e-143Fructose-bisphosphate aldolase FBA1 OS=Sugiyamaella lignohabitans GN=FBA1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1387

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 360

Detailed signature matches

  1. Family IPR000771
    Fructose-bisphosphate aldolase, class-II
    1. PS00602 (ALDOLASE_C...)
    2. TIGR00167
    3. PIRSF001359 (F_bP_a...)
    4. PF01116 (F_bP_aldolase)
    5. PS00806 (ALDOLASE_C...)
  2. Family IPR006411
    Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype
    1. TIGR01520
    2. cd00946 (FBP_aldola...)
  3. Domain IPR013785
    Aldolase-type TIM barrel
    1. G3DSA:3.20.20.70
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF51569 (Aldolase)

Residue annotation

  1. active site cd00946
  2. intersubunit inter...
  3. zinc binding site ...
  4. Na+ binding site c...

Protein sequence

>MCA_05532_1
MAVTDVLKRKSGVIVGDDVRALFEYAQKNKFAIPAVNVTSSSTVVAVLEAARDAKSPVILQTSQGGAAFFAGKGVDNKNQ
EASIAGAVAAAHYIRAIAPVYGIPVVLHSDHCAKKLLPWLDGMLEADEAYFKEHGEPLYSSHMIDLSEEPHEENIAITAK
YFERASKMNQWLEMEIGITGGEEDGVDNSGVESSKLYTQPNEVFEVYKALSPISPNFSIAAAFGNVHGVYKPGNVKLHPE
LLGKHQAYAKEQLKSDSDTPLFLVFHGGSGSAKEEFETAISFGVVKVNIDTDTQYAYLTGVRDFILNKKDYLMTQVGNPD
GDDKPNKKYFDPRVWVREGEKTMAKRVKESLEFFSTAGTL

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process
GO:0006096 glycolytic process

Molecular Function

GO:0003824 catalytic activity
GO:0004332 fructose-bisphosphate aldolase activity
GO:0008270 zinc ion binding
GO:0016832 aldehyde-lyase activity

Cellular Component

None predicted.