Protein

MCA_05528_1

Length
512 amino acids

Gene name: YAK1C

Description: Serine/threonine protein kinase similar to Yak1; in S. cerevisiae component of a glucose-sensing system that inhibits growth in response to glucose availability.

Browser: contigD:1558798-1560393-

RNA-seq: read pairs 352, FPKM 8.5, percentile rank 23.3% (100% = highest expression)

Protein function

Annotation:YAK1CSerine/threonine protein kinase similar to Yak1; in S. cerevisiae component of a glucose-sensing system that inhibits growth in response to glucose availability.
KEGG:K08827PRPF4B serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
EGGNOG:0PGRUPRP4kinase, PRP4
SGD closest match:S000003677YAK1Dual specificity protein kinase YAK1
CGD closest match:CAL0000193813YAK1Serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
MIA_03303_156.51%4075e-147MIA_03303_1
A0A1E3PQJ2_9ASCO56.59%3873e-139Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_39130 PE=4 SV=1
UniRef50_A0A1E3PQJ256.59%3878e-136Kinase-like protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PQJ2_9ASCO
A0A167D8N4_9ASCO52.40%4162e-138Serine/threonine protein kinase YAK1 OS=Sugiyamaella lignohabitans GN=YAK1 PE=4 SV=1
A0A060TFV0_BLAAD56.71%3652e-138ARAD1D17402p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17402g PE=3 SV=1
Q6C6A5_YARLI44.30%3951e-109YALI0E11077p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E11077g PE=4 SV=1
A0A1E4TKD6_9ASCO34.09%3523e-54Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12805 PE=3 SV=1
A0A0J9X4J9_GEOCN34.29%3502e-51Similar to Saccharomyces cerevisiae YJL141C YAK1 Serine-threonine protein kinase that is part of a glucose-sensing system OS=Geotrichum candidum GN=BN980_GECA02s05235g PE=4 SV=1
YAK1_YEAST38.63%2772e-46Dual specificity protein kinase YAK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YAK1 PE=1 SV=1
A0A1D8PH81_CANAL37.76%2412e-41Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YAK1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0571

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 512

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. mobidb-lite (disord...)

Protein sequence

>MCA_05528_1
MTENRSVNAKKHIMYDNSSTSSLSTPVTNPHDHIAKDNELDEIELRRKKRRLLLESLQENTSDSSSVNSSNSKPTETASR
NENSPNESVSSSPVSQNAPSSIKTILRNNNATPTKTHAKKDEDESDSDDMFADSPVEKLDISDQNTKSKVGKKLDSNLLD
NWNDVEGYYRIIPGELLDGKYLVTSTLGKGMFASVVRATDTSIQPTDGDNEALVAIKIIRNNETMFKAGLKELSIIQKLH
ELDPSNKQHVVKLIGSFDHKDHLCIVFENLNSNLRDLLKKFGREVGLNIQAIKSYARQLLLGLSLLKDAKIIHADLKPDN
ILVNDKHNVVKIADLGSACDITENNEITPYLVSRFYRAPELILGLEYSFGIDMWAIACTLYELYTGKMLFPGKTNNDMLR
LIMEARGKFSHKMLKKGKFVNQHFDENFDFKCLDQQQSRPNFDGTGSVPKTIKITGPKPECTIKAKLAGMEGKSGPNAKL
LTQFIDLLDQMLILNPEKRISPDNALKHPFCN

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.