Protein

MCA_05522_1

Length
639 amino acids

Gene name: SSA4C

Description: protein of the HSP70 family; has a role in SRP-dependent cotranslational protein-membrane targeting and translocation

Browser: contigD:1548320-1550240-

RNA-seq: read pairs 179, FPKM 3.5, percentile rank 14.6% (100% = highest expression)

Protein function

Annotation:SSA4Cprotein of the HSP70 family; has a role in SRP-dependent cotranslational protein-membrane targeting and translocation
KEGG:K03283HSPA1_8 heat shock 70kDa protein 1/8
EGGNOG:0PFQWHSP70heat shock
SGD closest match:S000000905SSA4Heat shock protein SSA4
CGD closest match:CAL0000184853SSA2Heat shock protein SSA2

Protein alignments

%idAln lengthE-value
MIA_05468_184.97%6120.0MIA_05468_1
A0A060TFE3_BLAAD83.93%6100.0ARAD1D14740p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D14740g PE=3 SV=1
A0A0J9X850_GEOCN83.11%6100.0Similar to Saccharomyces cerevisiae YBL075C SSA3 ATPase involved in protein folding and the response to stress OS=Geotrichum candidum GN=BN980_GECA04s07732g PE=3 SV=1
Q6C9V0_YARLI82.95%6100.0YALI0D08184p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D08184g PE=3 SV=1
A0A167C832_9ASCO83.11%6100.0Hsp70 family ATPase SSA3 OS=Sugiyamaella lignohabitans GN=SSA3 PE=3 SV=1
A0A1E3PCY5_9ASCO82.46%6100.0Heat shock protein 70 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44162 PE=3 SV=1
HSP72_CANAL81.31%6100.0Heat shock protein SSA2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SSA2 PE=1 SV=4
UniRef50_P4658781.31%6100.0Heat shock protein SSA2 n=714 Tax=Eukaryota TaxID=2759 RepID=HSP72_CANAL
A0A1E4TGS8_9ASCO80.16%6100.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2600 PE=3 SV=1
HSP74_YEAST78.52%6100.0Heat shock protein SSA4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSA4 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0794

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 639

Detailed signature matches

  1. Family IPR013126
    Heat shock protein 70 family
    1. PF00012 (HSP70)
    2. PR00301 (HEATSHOCK70)
  2. Domain IPR029047
    Heat shock protein 70kD, peptide-binding domain
    1. G3DSA:2.60.34.10
    2. SSF100920 (Heat sho...)
  3. Domain IPR029048
    Heat shock protein 70kD, C-terminal domain
    1. G3DSA:1.20.12...
    2. SSF100934 (Heat sho...)
  4. SITE IPR018181
    Heat shock protein 70, conserved site
    1. PS00297 (HSP70_1)
    2. PS01036 (HSP70_3)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.42...
  3. SSF53067 (Actin-lik...)
  4. cd10233 (HSPA1-2_6-...)
  5. mobidb-lite (disord...)

Residue annotation

  1. nucleotide binding...
  2. NEF/HSP70 interact...
  3. BAG/HSP70 interact...
  4. SBD interface cd10...

Protein sequence

>MCA_05522_1
MSKAIGIDLGTTYSCVAHYTNDRVEIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRKFSDPE
VQNDMKHFPFKIVDKAGKPAIQVEFKGETKIFHPEEILSMVLTKMKETAENHLGTKVTDVVISVPVYFNDSQRQAIKDAG
LIAGLNVLGIIKEPIAAAIAYGLDKKSSGEKNVLIFDFGGGIFDVSLLTIEDGIFEVKAVAGDTHLGGEDIDNKLVNLFI
QEFKRKNNKDISGNQRALRRLRTACEKAKRTLSSSTQATIEIDSFYEGIDFYSSITRARFEELCGDIFRSTFEPIEKVLR
DAKIDKSQVKDIVLVGGSTRIPKIQKLVSDFFNGKEPSKSINPDEAVAYGAAVQAAILSGDTSNTKTEDLLLFDVAPLSL
GIETAGGVMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVYEGERAKTKDNNLLGKFELSGIPPAPLGVPQIEVTFDID
ANCILNVSAVEMFTRNSNKITITNDKARFSKEDIERMVAEAEKYKEEDEKKAARMKAINGLESYANSLKNTISEANFKEK
VSEADREKLNKAIKETIDWLDNNQTATTEEFSDHQKELEGIANPIMTSFYSDAEILPNMPGAGSSTSLAGGDSTVEKAD

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.