Protein

MCA_05473_1

Length
472 amino acids


Gene name: RVS167

Description: Calmodulin-binding actin-associated protein; roles in endocytic membrane tabulation and constriction, and exocytosis

Browser: contigD:1409936-1411583+

RNA-seq: read pairs 4646, FPKM 121.4, percentile rank 82.0% (100% = highest expression)

Protein function

Annotation:RVS167Calmodulin-binding actin-associated protein; roles in endocytic membrane tabulation and constriction, and exocytosis
KEGG:K12562AMPH amphiphysin
EGGNOG:0QE91PGUG_04307Reduced viability upon starvation protein
SGD closest match:S000002796RVS167Reduced viability upon starvation protein 167
CGD closest match:CAL0000200028RVS167Regulator of cytoskeleton and endocytosis RVS167

Protein alignments

%idAln lengthE-value
A0A0J9X734_GEOCN87.50%2961e-176Similar to Saccharomyces cerevisiae YDR388W RVS167 Actin-associated protein with roles in endocytosis and exocytosis OS=Geotrichum candidum GN=BN980_GECA04s02232g PE=4 SV=1
MIA_05855_182.59%2932e-159MIA_05855_1
A0A161HM26_9ASCO84.78%2767e-159Amphiphysin OS=Sugiyamaella lignohabitans GN=RVS167 PE=4 SV=1
A0A1E3PKQ1_9ASCO75.42%2979e-154Actin-associated protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46235 PE=4 SV=1
Q6C963_YARLI73.06%2975e-148YALI0D13706p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D13706g PE=4 SV=1
A0A060TBE5_BLAAD83.33%2345e-140ARAD1D34606p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D34606g PE=4 SV=1
UniRef50_D4ANC269.68%2772e-128Uncharacterized protein n=93 Tax=Ascomycota TaxID=4890 RepID=D4ANC2_ARTBC
RV167_CANAL65.86%2901e-131Regulator of cytoskeleton and endocytosis RVS167 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RVS167 PE=3 SV=2
RV167_YEAST64.75%2951e-130Reduced viability upon starvation protein 167 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RVS167 PE=1 SV=1
A0A1E4TFC6_9ASCO65.49%2842e-126Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2107 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9620

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 472

Detailed signature matches

    1. SSF103657 (BAR/IMD ...)
    1. PS51021 (BAR)
    2. SM00721 (5bar)
    3. PF03114 (BAR)
    1. PF00018 (SH3_1)
    2. SM00326 (SH3_2)
    3. SSF50044 (SH3-domain)
    4. PR00452 (SH3DOMAIN)
    5. PS50002 (SH3)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd07599 (BAR_Rvs167p)
  2. mobidb-lite (disord...)

Residue annotation

  1. dimer interface cd...

Protein sequence

>MCA_05473_1
MSWKGFTKSVSRAPQSFRQKFNMGPQTKDPVYIDAERRFKELETETKKLHEESKKYFEAINGMLSHQIEFSRAVEEVYKP
ISGRMSDPNSTKPEGNPEGIQACEQYRDVVRELQETLKPELEMIETRIIGPADELLRVIKAIRKMATKRDHKQLDLDRHT
NTLTKLQNKKERSTKDEKNLYTAENNVEIATQEFNYFNDMLKEELPKLFQYEAEFIRPLFQNFYYMQLNIFYTLYTRMEE
MKIPYFDLVSDIETSFNEKRGDIQEQTEAIGITHFRVGHAKAKLELTRKKFGKETEAEASSAASPANSAAPPPYDPSGYA
QQPVYGQQPAYGQQPAYGQQPAYGQPPVGAAVPGYGVPPATAAAGVPPSYGQPGTVLAAGPAAYGDVKAQPTGYGDVKAP
LPPAPAPAAPAAAPGVEYCVALYDYAPQAQGDLALKAGDVIEIVQKTDANGWWTGKLNGQQGVFPGNYVQLR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

GO:0005737 cytoplasm