Protein

MCA_05464_1

Length
690 amino acids


Gene name: CLF1

Description: Pre-mRNA-splicing factor CLF1

Browser: contigD:1387816-1389955+

RNA-seq: read pairs 425, FPKM 7.6, percentile rank 21.7% (100% = highest expression)

Protein function

Annotation:CLF1Pre-mRNA-splicing factor CLF1
KEGG:K12869CRN crooked neck
EGGNOG:0PFU9CLF1Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity)
SGD closest match:S000004107CLF1Pre-mRNA-splicing factor CLF1
CGD closest match:CAL0000187187CLF1Pre-mRNA-splicing factor CLF1

Protein alignments

%idAln lengthE-value
MIA_01819_174.78%6700.0MIA_01819_1
A0A161HJ29_9ASCO72.11%6670.0Clf1p OS=Sugiyamaella lignohabitans GN=CLF1 PE=4 SV=1
UniRef50_A0A161HJ2972.11%6670.0Clf1p n=3 Tax=saccharomyceta TaxID=716545 RepID=A0A161HJ29_9ASCO
A0A0J9XJ80_GEOCN71.53%6780.0Similar to Saccharomyces cerevisiae YLR117C CLF1 Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2,U5, and U6 snRNAs OS=Geotrichum candidum GN=BN980_GECA20s01055g PE=4 SV=1
A0A1E3PT36_9ASCO62.72%6840.0Pre-mRNA-splicing factor CLF1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_63996 PE=4 SV=1
A0A060SZ70_BLAAD63.29%6620.0ARAD1C06072p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06072g PE=4 SV=1
CLF1_YARLI62.99%6620.0Pre-mRNA-splicing factor CLF1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CLF1 PE=3 SV=1
A0A1E4TBC5_9ASCO42.92%6780.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32441 PE=4 SV=1
CLF1_CANAL39.91%6895e-161Pre-mRNA-splicing factor CLF1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CLF1 PE=3 SV=3
CLF1_YEAST39.45%6596e-157Pre-mRNA-splicing factor CLF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLF1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0613

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Repeat
1 100 200 300 400 500 600 690

Detailed signature matches

    1. SSF48452 (TPR-like)
    1. PS50293 (TPR_REGION)
    1. SM00386 (hat_new_1)
    2. PF02184 (HAT)
Unintegrated signatures no IPR
Unintegrated signatures

Protein sequence

>MCA_05464_1
MSENSRYKVKNKAVAELQISAEQILLEAYERKEQPLVIPEQKITDLEELSEYQGRKRREYEDALRRNRQNFGQWMRYAQW
ELDHEEYDRARSIFERALDVDSTNVPLWIRYIKSELKTRNINHARNLLDRAVTILPRIDKLWFTYVQVEETLLNIPGCRQ
VFERWMEWRPEPPAWNAYINMEKRYGEYDRARNIFQRFTALYPQPENWIKWAQFEEEFGTAENVREVYTMGVDTLMAAGD
EFLDERIFAAWAKWESKQREWERARAIYQFGLQRLSKSKSASLYNSYLSFTKQYGEKDGIEDAILAKRRIKYEDNLKEDP
HDYDTWFSYLTLLEESSADPSETRDVYERAIANIPEQKEKRFWRRYIFLWIRYAIYEELTTKDIERTRQIYQQCIKIIPH
KNFSFDKIWILYAKFEIRQNNLQKARKILGQGLALSGKPKIYKNYIQIEKDLKEFDRCRILYQKYIEKYPDFPSPWIEFA
EMEQMLGDLDRARAIFELAIEQEEMEMPELVWKRYINFETEEEEYDRARALYEKLIELTGHVKVWISYALFEISIPDSNQ
QTEDNEEDEEVEIEVSEEAKSRARKIFERAWDYFKKENKSEERVILNESWKDFEAVHGNDSTKEKVEKQTPYMVKKTKRL
PDGSYTEYNDYVFPTDNEDKDKSRDFSAFLANAKKWKAAAAAKAPQNTSS

GO term prediction

Biological Process

GO:0006396 RNA processing

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.