Protein

MCA_05459_1

Length
1,063 amino acids

Browser: contigD:1368658-1371850-

RNA-seq: read pairs 1316, FPKM 15.3, percentile rank 34.6% (100% = highest expression)

Protein function

SGD closest match:S000001204YAP1801Clathrin coat assembly protein AP180A
CGD closest match:CAL0000184462orf19.4184Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_01965_174.69%3204e-168MIA_01965_1
A0A0J9X3A3_GEOCN59.43%2125e-73Similar to Saccharomyces cerevisiae YHR161C YAP1801 Protein involved in clathrin cage assembly OS=Geotrichum candidum GN=BN980_GECA01s08282g PE=4 SV=1
UniRef50_A0A0J9X3A359.43%2121e-69Similar to Saccharomyces cerevisiae YHR161C YAP1801 Protein involved in clathrin cage assembly n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X3A3_GEOCN
A0A060TAJ9_BLAAD40.68%3226e-54ARAD1D27588p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27588g PE=4 SV=1
A0A1E4TD15_9ASCO25.82%3375e-21Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_148580 PE=4 SV=1
A0A1E3PEB8_9ASCO24.43%3077e-17ANTH-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48050 PE=4 SV=1
AP18A_YEAST25.16%3149e-16Clathrin coat assembly protein AP180A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YAP1801 PE=1 SV=1
Q6CF76_YARLI23.76%3033e-14YALI0B09603p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B09603g PE=4 SV=1
A0A1D8PL36_CANAL24.18%3069e-13Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4184 PE=4 SV=1
A0A167E4S4_9ASCO24.32%1854e-08Yap1801p OS=Sugiyamaella lignohabitans GN=YAP1801 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0854

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 900 1000 1063

Detailed signature matches

  1. Domain IPR008942
    ENTH/VHS
    1. SSF48464 (ENTH/VHS ...)
    2. G3DSA:1.25.40.90
  2. Domain IPR013809
    ENTH domain
    1. PS50942 (ENTH)
  3. Domain IPR011417
    AP180 N-terminal homology (ANTH) domain
    1. PF07651 (ANTH)
  4. Domain IPR014712
    Phosphoinositide-binding clathrin adaptor, domain 2
    1. G3DSA:1.20.58...
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF89009 (GAT-like ...)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_05459_1
MSSMVEGSNISISKAVKGATKPKEAPPKDKYIYAIRAFVSSNPHPEVPYAQLSRLLVPKLNSPSLIVSLKAHLVFHQLIS
DANAPKYIFLTYISKHYATANRSSVDCTTFDIINDFRNFNRQQALPNLAHAIPQSIDTNRLVSAYNRYLRERILHFKFLK
MDPIREKIDGNSLVDTTQRHKLHLPESSADLLNQIQCSIQQIRLILACIFTPASLNHPLYSYCYGLVSMDLSILFRFINL
ALVAALQNFFSLPRECSERTLFAYKEYTQLQLAEEVHTFINMGPNAVSPKDLEIPGPLRQDEQAVKQLTKSLEDFLYASK
EKENRASSSTQNNHSRMTKSDSSSSLSSSTSSDFSSSSLNSMNSMSSENLHQRDGLSSGHTSAGSARFNPYANPQNKPVA
PSVISKDEYLRLSVATNRTSSSNSNISHQKVNLNTTNGKSSTKHEIANSPVVEDRRMEIPNKSFLRETQSSNNLRSQSPS
ANHDSQSLRSNLSQMSTVSKNNNNINSNNNNNNNNNNNNPYMNPQNLKFTGSESTIKPRTVSTASSTFSDSPDAPTPKAH
SIQKHFDTPKSNEYLSGNPSIPVLSTAALSGDLPETKPLSSIKKNGFLSNVPPSAPPTSALPMPPLVPGGRTLSAKSSAS
SLKIAKDSVPPNPVESPSSSTFSPSPDRRNSNSKNSYQNVDYSSLPLPPPPPPSSSHQPNRSGSVSSVKSSRAPSVHQHQ
QQQQRTLSKSKSAANLKYHNSNVKNHHHYEDSSFNNSHSSASRTPSKADFVSSNSTHKSSSTNNTTQSAQTRSTGNTSSS
TNGDTKSSRNDSKDVTDPSTLPEGFDPNDPSMENWQKLLDTLDHPEATFSLKFDLASALQRSIAFNEKAGKLLSNQEIPP
VPDMPANAHELTATNTNATTNTTTNASIKKSNSGHGFSSKLKAVGENIKHPKNHYYNNNNHGSSLSSNHDETQQLSKEQQ
QTTTVTIPRSQSQENYEKYNNEYRKNLMQSAISSSSSSSPPSQEYSNNNSIINHSTNSSISSSSNQQKNHYSENYSTSNN
NSNTKTKKKAPGFLIKSFRKVAT

GO term prediction

Biological Process

GO:0048268 clathrin coat assembly

Molecular Function

GO:0005543 phospholipid binding
GO:0005545 1-phosphatidylinositol binding
GO:0030276 clathrin binding

Cellular Component

GO:0030136 clathrin-coated vesicle