Protein

MCA_05457_1

Length
349 amino acids

Gene name: ADH2

Description: Alcohol dehydrogenase 2

Browser: contigD:1363425-1364475-

RNA-seq: read pairs 149, FPKM 5.3, percentile rank 17.9% (100% = highest expression)

Protein function

Annotation:ADH2Alcohol dehydrogenase 2
KEGG:K13953adhP alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
EGGNOG:0PH61ADH1alcohol dehydrogenase
SGD closest match:S000004918ADH2Alcohol dehydrogenase 2
CGD closest match:CAL0000200753ADH2Alcohol dehydrogenase 2

Protein alignments

%idAln lengthE-value
MIA_05395_182.23%3490.0MIA_05395_1
A0A0J9XBV1_GEOCN73.71%3502e-174Similar to Saccharomyces cerevisiae YMR083W ADH3 Mitochondrial alcohol dehydrogenase isozyme III OS=Geotrichum candidum GN=BN980_GECA07s02870g PE=3 SV=1
UniRef50_A0A1V2L2I461.96%3473e-148Alcohol dehydrogenase 4, mitochondrial n=1 Tax=Cyberlindnera fabianii TaxID=36022 RepID=A0A1V2L2I4_CYBFA
ADH2_YEAST58.50%3473e-152Alcohol dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH2 PE=1 SV=3
ADH2_CANAL58.50%3472e-149Alcohol dehydrogenase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADH2 PE=3 SV=1
A0A167FJP5_9ASCO60.98%3462e-148Alcohol dehydrogenase ADH3 OS=Sugiyamaella lignohabitans GN=ADH3 PE=3 SV=1
Q6CGT5_YARLI62.00%3502e-147YALI0A16379p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A16379g PE=3 SV=1
A0A060TBM3_BLAAD61.10%3472e-146ARAD1B16786p OS=Blastobotrys adeninivorans GN=AADH1 PE=3 SV=1
A0A1E4TA62_9ASCO60.00%3504e-141Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_126711 PE=3 SV=1
A0A1E3PCI4_9ASCO56.94%3462e-138Alcohol dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48354 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0232

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 349

Detailed signature matches

  1. Domain IPR011032
    GroES-like
    1. SSF50129 (GroES-like)
  2. Domain IPR020843
    Polyketide synthase, enoylreductase domain
    1. SM00829 (PKS_ER_nam...)
  3. Domain IPR013154
    Alcohol dehydrogenase, N-terminal
    1. PF08240 (ADH_N)
  4. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  5. Domain IPR013149
    Alcohol dehydrogenase, C-terminal
    1. PF00107 (ADH_zinc_N)
  6. SITE IPR002328
    Alcohol dehydrogenase, zinc-type, conserved site
    1. PS00059 (ADH_ZINC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. G3DSA:3.90.18...
  3. cd08297 (CAD3)

Residue annotation

  1. catalytic Zn bindi...
  2. substrate binding ...
  3. NAD binding site c...
  4. tetramer interface...
  5. structural Zn bind...

Protein sequence

>MCA_05457_1
MSPIPKTQKAMVIDKPNAPLQYRDVPVPTPKNDELLVHIQYSGACHSDLHAWKADWPFPTPFPLIGGHEGTGVVVAKGEG
ATNFEIGDKVGVKWINGTCLDCRFCLQGAEGNCPKGSYSGFTTPGTFQQYTTVKAAHAARIPEGVDMAMAAPILCAGVTV
YKALKRSDAKAGESVVITGAGGGLGSLAVQYAHAMGFRVIGIDTGDAKRDLVLKSGGEVFVDFMKDDVTKKVLEATDGEG
AQAVIHVAVSEKAVETSLEYVRATGTIVLVGLPADAVVHSPVFPHVIRAITIRGSLVGNREDTVEAMDFVRRGLVKTPIK
IVGLTELPHVYELMEKGQIAGRYVLDTSK

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.