Protein

MCA_05456_1

Length
519 amino acids

Browser: contigD:1361200-1362760-

RNA-seq: read pairs 9958, FPKM 236.6, percentile rank 90.0% (100% = highest expression)

Protein function

EGGNOG:0PGT9FG09960.1Aldehyde dehydrogenase
SGD closest match:S000004716HFD1Fatty aldehyde dehydrogenase HFD1
CGD closest match:CAL0000181570orf19.6066Aldehyde dehydrogenase

Protein alignments

%idAln lengthE-value
MIA_05393_163.62%5030.0MIA_05393_1
A0A0J9X635_GEOCN55.96%5200.0Aldehyde dehydrogenase OS=Geotrichum candidum GN=BN980_GECA02s07941g PE=3 SV=1
UniRef50_A0A0J9X63555.96%5200.0Aldehyde dehydrogenase n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X635_GEOCN
Q6C5T1_YARLI46.60%5153e-165Aldehyde dehydrogenase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E15400g PE=3 SV=1
A0A1E3PGL7_9ASCO49.90%5052e-164Aldehyde dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52192 PE=3 SV=1
A0A060T783_BLAAD46.41%5156e-164Aldehyde dehydrogenase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C26510g PE=3 SV=1
A0A167CJH4_9ASCO46.44%5193e-161Aldehyde dehydrogenase OS=Sugiyamaella lignohabitans GN=HFD1 PE=3 SV=1
A0A1D8PC76_CANAL46.45%4933e-148Aldehyde dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6066 PE=3 SV=1
A0A1E4TAK0_9ASCO39.05%4842e-113Aldehyde dehydrogenase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_128575 PE=3 SV=1
HFD1_YEAST39.62%4771e-89Fatty aldehyde dehydrogenase HFD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HFD1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0644

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 519

Detailed signature matches

  1. Family IPR012394
    Aldehyde dehydrogenase NAD(P)-dependent
    1. PIRSF036492 (ALDH)
  2. Domain IPR016162
    Aldehyde dehydrogenase N-terminal domain
    1. G3DSA:3.40.60...
  3. Domain IPR016161
    Aldehyde/histidinol dehydrogenase
    1. SSF53720 (ALDH-like)
  4. Domain IPR015590
    Aldehyde dehydrogenase domain
    1. PF00171 (Aldedh)
  5. SITE IPR029510
    Aldehyde dehydrogenase, glutamic acid active site
    1. PS00687 (ALDEHYDE_D...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.40.30...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. cd07135 (ALDH_F14-Y...)

Residue annotation

  1. NAD(P) binding sit...
  2. catalytic residues...

Protein sequence

>MCA_05456_1
MSYTISSYEDIPEITPMEEIPKLINRVQSGFRSHRTISLEYRKEQLRNLYYAVLDNYDVLKEAVHKDLHKPPHETDLTEL
FYVSNEIRWFIENLDTIAKPEKIKEVPLTLKLATGRIYKQPFGTVLIISPWNYPIGLSISPITAAIAAGNTVVFKPSEVS
VNTSKALVKVLSKALDPEIFVGITGAVPEITEILKYKFDKIMYTGNGAVGRIISHAAAEHLTPVILELGGKSPVVVTKTA
DLRIAARRVLWGKQTNSGQTCVAPDYCLVDESIKSDFIKQLKIAYEEFDKNLDPNSPSYSHIISDRHFHRLKKYLDETKG
DIILGGKSDAETRFFAPTIVDNVTASDSLMKEELFGPLLGLVSYKTLDEAVEFITKEHDTPLALYIFSTDKNEKKFILDR
VRSGGVSINDTLMHLTFLHAPFGGIGESGSGSYHGIFGYKAFTHERTVLDQPGFVEFALDVRYPPYSESKNKQFALINGP
VKNPFPRTGPIKKSFFQQYLNKFFWFFVILGAVAFKFKK

GO term prediction

Biological Process

GO:0006081 cellular aldehyde metabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.