Protein
MCA_05397_1
Length
377 amino acids
Gene name: PHA2
Description: Putative prephenate dehydratase
Browser: contigD:1226550-1227761+
RNA-seq: read pairs 395, FPKM 12.9, percentile rank 30.8% (100% = highest expression)
Protein function
| Annotation: | PHA2 | Putative prephenate dehydratase | |
|---|---|---|---|
| KEGG: | K04518 | pheA2 | prephenate dehydratase [EC:4.2.1.51] |
| EGGNOG: | 0PJU6 | PHA2 | Prephenate dehydratase |
| SGD closest match: | S000005260 | PHA2 | Putative prephenate dehydratase |
| CGD closest match: | CAL0000185001 | PHA2 | Prephenate dehydratase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02519_1 | 44.84% | 417 | 6e-108 | MIA_02519_1 |
| UniRef50_A0A1E4S020 | 32.53% | 372 | 3e-44 | PDT-domain-containing protein n=4 Tax=Phaffomycetaceae TaxID=115784 RepID=A0A1E4S020_CYBJA |
| A0A1E3PFT2_9ASCO | 34.15% | 369 | 2e-45 | PDT-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_43699 PE=4 SV=1 |
| A0A060TCB5_BLAAD | 31.96% | 363 | 4e-42 | ARAD1D40304p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D40304g PE=4 SV=1 |
| A0A0J9XBG0_GEOCN | 32.52% | 329 | 8e-39 | Similar to Saccharomyces cerevisiae YNL316C PHA2 Prephenate dehydratase catalyzes the conversion of prephanate to phenylpyruvate OS=Geotrichum candidum GN=BN980_GECA08s00758g PE=4 SV=1 |
| PHA2_YEAST | 29.05% | 389 | 3e-34 | Putative prephenate dehydratase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PHA2 PE=1 SV=3 |
| Q6CEA0_YARLI | 27.40% | 365 | 5e-34 | YALI0B17336p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B17336g PE=4 SV=1 |
| A0A1D8PJH8_CANAL | 27.70% | 379 | 1e-28 | Prephenate dehydratase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PHA2 PE=4 SV=1 |
| A0A1E4TIQ0_9ASCO | 24.86% | 362 | 4e-27 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_23540 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0076
Protein family membership
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
377
Detailed signature matches
-
-
PIRSF001500 (Chor_m...)
-
no IPR
Unintegrated signatures
Residue annotation
-
active site cd13532
-
dimer interface cd...
Protein sequence
>MCA_05397_1 MTESQKLKLAYLGPKGTYSHESAMRFADLLDKDFQETLEYSPIPTISQCLEELVSGTVDFAVIPFENVTNGTVVPACDTI RDLIHNAPQNTTNQYTAQPLQDYPYRNTNIPTLINEVFVPIQHCLLSFAPSIEQVSRLYTHPQAWGQVTGFLDSVFDEKK VPRIDTSSTSAAAALVTREEAEKRFASEDADMELKPTDIASGHELSSANNTNEKFCAAIASRAASKVHNVPILQPDISNF SSNTTRFLVFTKPGFDLKSTKYKAQNINKQEYLTLLGITITQADPTAFSKCLEALISNNVNIVSMKCRPSQSLASKSLQN SETESSNTSWQTLYYIEISGSVYTDENVQKAISTIKSHTNRLTVFGQFPRAPEYYLK
GO term prediction
Biological Process
GO:0009094 L-phenylalanine biosynthetic process
Molecular Function
GO:0004106 chorismate mutase activity
GO:0004664 prephenate dehydratase activity
Cellular Component
GO:0005737 cytoplasm