Protein

MCA_05395_1

Length
551 amino acids

Gene name: DPS1

Description: Aspartate--tRNA ligase, cytoplasmic

Browser: contigD:1223472-1225490-

RNA-seq: read pairs 12852, FPKM 287.7, percentile rank 91.5% (100% = highest expression)

Protein function

Annotation:DPS1Aspartate--tRNA ligase, cytoplasmic
KEGG:K01876DARS aspartyl-tRNA synthetase [EC:6.1.1.12]
EGGNOG:0PFAWDPS1Aspartyl-tRNA synthetase
SGD closest match:S000003941DPS1Aspartate--tRNA ligase, cytoplasmic
CGD closest match:CAL0000190946DPS1-1Aspartate--tRNA ligase

Protein alignments

%idAln lengthE-value
MIA_02485_185.92%5610.0MIA_02485_1
A0A0J9XC81_GEOCN81.44%5550.0Similar to Saccharomyces cerevisiae YLL018C DPS1 Aspartyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA10s00373g PE=3 SV=1
A0A1E3PIZ1_9ASCO72.70%5640.0Aspartyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47084 PE=3 SV=1
Q6C868_YARLI72.34%5640.0YALI0D22264p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D22264g PE=3 SV=1
A0A167EVX0_9ASCO72.73%5610.0Aspartate--tRNA ligase DPS1 OS=Sugiyamaella lignohabitans GN=DPS1 PE=3 SV=1
A0A060T5K8_BLAAD70.22%5540.0ARAD1B07480p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B07480g PE=3 SV=1
Q59UF7_CANAL72.65%4900.0Aspartate--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DPS1-1 PE=3 SV=1
UniRef50_B9WLB972.45%4900.0Aspartyl-tRNA synthetase, cytoplasmic, putative n=7 Tax=Debaryomycetaceae TaxID=766764 RepID=B9WLB9_CANDC
SYDC_YEAST71.17%4890.0Aspartate--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DPS1 PE=1 SV=3
A0A1E4TDV1_9ASCO70.72%4850.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31018 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0916

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 551

Detailed signature matches

  1. Family IPR002312
    Aspartyl/Asparaginyl-tRNA synthetase, class IIb
    1. PR01042 (TRNASYNTHASP)
  2. Family IPR004523
    Aspartate-tRNA synthetase, type 2
    1. TIGR00458
    2. MF_02075 (Asp_tRNA_...)
  3. Domain IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249 (Nucleic a...)
  4. Domain IPR006195
    Aminoacyl-tRNA synthetase, class II
    1. PS50862 (AA_TRNA_LI...)
  5. Domain IPR004364
    Aminoacyl-tRNA synthetase, class II (D/K/N)
    1. PF00152 (tRNA-synt_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:2.40.50...
  3. G3DSA:3.30.93...
  4. SSF55681 (Class II ...)
  5. cd00776 (AsxRS_core)
  6. cd04320 (AspRS_cyto_N)
  7. mobidb-lite (disord...)

Residue annotation

  1. dimer interface cd...
  2. anticodon binding ...
  3. homodimer interfac...
  4. motif 1 cd00776
  5. motif 2 cd00776
  6. active site cd00776
  7. motif 3 cd00776

Protein sequence

>MCA_05395_1
MAEQITQKTEDLKISDAAAPPLGPDGQPLSKKALKKLEAARLKEQKKAETAARLAAEQAAREAAEPDYGTENYGVLPLIQ
STTKSGIERIKINTLSKENAGQTVVFRARVHTSRQQGSKMNFMTFRQQNSLIQGLVAVNADSISKKMVKWSASINLESIV
LVHGVVVAAPEEITSCTVKDAEIQVSKLYVISGAPAQLPILIEDASRSEEEAEKAGLPVVNLDTRLDYRVIDLRTVTNQA
IFRITSGVCTLFREYLLNKGFVEIHTPKLMGAPSEGGANVFKVQYFKGDAYLAQSPQLAKQMLIAADFEKVFEIAPVFRA
ENSNTARHMTEFTGLDLEMAFEEHYDEVIDTLVDMFMFIFNGLKTRFADEIAVVRKQYPVEEFKLPKDGKMVRIPFKEGI
KMLREAGEDVPDLEDLSTPHEKLLGKLVHDKYDTDFYILDKFPLAVRPFYTMPDPEDPQYSNSYDFFMRGEEILSGAQRI
HDSKLLSERMKAHEVDPTSDGLKDYVDAFSYGAPPHGGGGIGLERVVMFYLGLGNIRRASLFPRDPRRLRP

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006422 aspartyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004815 aspartate-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm