Protein

MCA_05392_1

Length
361 amino acids

Gene name: ECM4

Description: Glutathione S-transferase omega-like 2

Browser: contigD:1215658-1216893+

RNA-seq: read pairs 15226, FPKM 519.7, percentile rank 94.4% (100% = highest expression)

Protein function

Annotation:ECM4Glutathione S-transferase omega-like 2
KEGG:K07393ECM4 glutathionyl-hydroquinone reductase [EC:1.8.5.7]
EGGNOG:0PFDCECM4glutathione s-transferase
SGD closest match:S000001784ECM4Glutathione S-transferase omega-like 2
CGD closest match:CAL0000196854ECM4Omega-class glutathione transferase

Protein alignments

%idAln lengthE-value
A0A0J9XKU8_GEOCN74.46%3253e-180Similar to Saccharomyces cerevisiae YGR154C GTO1 Omega-class glutathione transferase OS=Geotrichum candidum GN=BN980_GECA32s02342g PE=4 SV=1
MIA_02772_173.80%3134e-177MIA_02772_1
A0A1E3PJQ5_9ASCO69.66%3231e-166Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46262 PE=4 SV=1
Q6CDX7_YARLI67.73%3133e-156YALI0B20416p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B20416g PE=4 SV=1
A0A167FU43_9ASCO67.69%2944e-147Ecm4p OS=Sugiyamaella lignohabitans GN=ECM4 PE=4 SV=1
UniRef50_C8VMA863.90%3139e-140Glutathione S-transferase (Eurofung) n=52 Tax=leotiomyceta TaxID=716546 RepID=C8VMA8_EMENI
A0A060T3C2_BLAAD60.55%3274e-143ARAD1C31680p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C31680g PE=4 SV=1
A0A1D8PS56_CANAL60.75%3212e-141Omega-class glutathione transferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ECM4 PE=4 SV=1
A0A1E4TM64_9ASCO59.68%3152e-137Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147691 PE=4 SV=1
GTO2_YEAST48.75%3612e-110Glutathione S-transferase omega-like 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM4 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9946
Predicted cleavage: 19

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 361

Detailed signature matches

  1. Family IPR016639
    Glutathione S-transferase (GST)
    1. PIRSF015753 (GST)
  2. Domain IPR012336
    Thioredoxin-like fold
    1. SSF52833 (Thioredox...)
  3. Domain IPR004045
    Glutathione S-transferase, N-terminal
    1. PF13409 (GST_N_2)
  4. Domain IPR010987
    Glutathione S-transferase, C-terminal-like
    1. SSF47616 (GST C-ter...)
    2. PS50405 (GST_CTER)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.10...
  3. G3DSA:3.40.30.10
  4. PF13410 (GST_C_2)
  5. SFLDG01148 (Xi_(cyt...)
  6. cd03190 (GST_C_Omeg...)

Residue annotation

  1. SFLDG01148
  2. putative dimer int...
  3. N-terminal domain ...
  4. putative substrate...

Protein sequence

>MCA_05392_1
MLFSSFLKRTITSQFSKSIISTSNSISIPSTVSFTRNFNSTMPNAKPEQTSGNFADKDGHFKRKPSSFRNTISSEPGAEF
PPEKGRYHLYVSLACPWAHRTLITRKLKGLEDIISVNVVDWFMGENGWRFTTPDKVPGSTPDELYGSEYIKDIYFKADPK
YEGRFTVPILWDKKKETIVNNESSEIIRIFYTQFDDIIDEKYKGVTYYPEKYAEKIDELNSWIYDDINNGVYKSGFATTQ
EAYEQNVKQLFKSLDKVEEILGKNKYLTGDEFTEADLRLYPTIVRFDPVYVQHFKCNIGMIRYNYPNIDKWLRKLYWEND
AFKSTTNFDHIKYHYTKSHLKYNPYGITPVGPLPHILPKIE

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.