Protein
MCA_05326_1
Length
710 amino acids
Gene name: AFG1B
Description: Protein AFG1; may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane
Browser: contigD:1019211-1021344-
RNA-seq: read pairs 2470, FPKM 42.9, percentile rank 62.0% (100% = highest expression)
Protein function
| Annotation: | AFG1B | Protein AFG1; may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane | |
|---|---|---|---|
| EGGNOG: | 0PJPH | FG09964.1 | AFG1-like ATPase |
| SGD closest match: | S000000778 | AFG1 | Protein AFG1 |
| CGD closest match: | CAL0000193419 | AFG1 | Afg1p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05290_1 | 54.20% | 727 | 0.0 | MIA_05290_1 |
| A0A0J9X789_GEOCN | 49.65% | 715 | 0.0 | Similar to Saccharomyces cerevisiae YEL052W AFG1 Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits OS=Geotrichum candidum GN=BN980_GECA04s03332g PE=4 SV=1 |
| UniRef50_A0A0J9X789 | 49.65% | 715 | 0.0 | Similar to Saccharomyces cerevisiae YEL052W AFG1 Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X789_GEOCN |
| Q6C5Q5_YARLI | 42.60% | 709 | 1e-173 | YALI0E16126p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E16126g PE=4 SV=1 |
| A0A1E3PGL4_9ASCO | 41.94% | 713 | 3e-168 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47569 PE=4 SV=1 |
| A0A1E4TFN0_9ASCO | 40.98% | 693 | 2e-157 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_107844 PE=4 SV=1 |
| A0A1D8PEE3_CANAL | 35.18% | 739 | 5e-132 | Afg1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AFG1 PE=4 SV=1 |
| AFG1_YEAST | 29.10% | 457 | 3e-41 | Protein AFG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AFG1 PE=1 SV=1 |
| A0A060T7W9_BLAAD | 30.94% | 320 | 2e-40 | ARAD1C31394p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C31394g PE=4 SV=1 |
| A0A167EM36_9ASCO | 29.27% | 328 | 5e-38 | Afg1p OS=Sugiyamaella lignohabitans GN=AFG1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9112
Predicted cleavage: 28
Protein family membership
- ATPase, AFG1-like (IPR005654)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
710
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
cd00009 (AAA)
-
mobidb-lite (disord...)
Residue annotation
-
Walker A motif cd0...
-
ATP binding site c...
-
Walker B motif cd0...
Protein sequence
>MCA_05326_1 MYRYRSTIVLHGPKHLVRVLSARLYSTTSLALTDPLHIYQQKVATGELYPDEAQFRAAVELQKLSERLIDYNPPPNFKHR IRELSRLIEKREEEERAREILAEKYAKEHPEATKEEDGIFKRVKRAWYMPDEQSNQIIKQLSDEQELFNSTAPQGLLLYG EVGCGKSMLIDLFYDSLPNISKRRLHYNNFMLGLYAHIHKVSEERLRGSKRLSKLRLQNDFILLQLAEKMVDENPILLLD EFMLPDIAAAKIVQTLFTFFFKLGGVLVATSNRLPEELYATEFRKEQFETFFRILKSRCVAYDMRSNNDWRVLLSEKESE LKKLDSELNLDHEKPELGGEHTNYFVLNTDENEDKWAYILQDLTTDLKTSHPDEVIVYGHKVQVPWANEGVAYFQFDDIC KSYLSAPDYISLASRYHTFIIDNIPALTIYQKNEARRFITLLDALYESKCKLVIRADVPPEDLFFKDAREEELESDDVGA QETFAKAYQDLENPFRPNVASYDETSDFKDDPSSTAKPTKITPPPQAPNKYHNNNDESYLTTSIAQDVASNENSKTTPNF RKTSAFTGEDEKFAYKRAVSRLKEMTGSKSWLTEREWSPIPREDRPWETFEETKPLPESYFKLTGKQTEEANSSEPESKA TQQPVEQDYEDDISRYSSPFKKRLVEAPKFDAQHFWAMVEWGPGSRLKDKIAKEWIKSNNAYTRDQDSDK
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005524 ATP binding
Cellular Component
None predicted.