Protein

MCA_05320_1

Length
368 amino acids

Gene name: SDT1

Description: Suppressor of disruption of TFIIS

Browser: contigD:1006154-1007261-

RNA-seq: read pairs 2406, FPKM 80.6, percentile rank 75.4% (100% = highest expression)

Protein function

Annotation:SDT1Suppressor of disruption of TFIIS
KEGG:K18551SDT1 pyrimidine and pyridine-specific 5'-nucleotidase [EC:3.1.3.-]
EGGNOG:0PJ6VPGUG_03061Pyrimidine 5'-nucleotidase
SGD closest match:S000003192SDT1Suppressor of disruption of TFIIS
CGD closest match:CAL0000194158orf19.3922Nucleotidase

Protein alignments

%idAln lengthE-value
MIA_01550_158.44%3853e-146MIA_01550_1
A0A060SXW5_BLAAD62.84%2181e-101ARAD1A15664p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A15664g PE=4 SV=1
A0A0J9XLG1_GEOCN60.37%2178e-93Similar to Saccharomyces cerevisiae YGL224C SDT1 Pyrimidine nucleotidase OS=Geotrichum candidum GN=BN980_GECA32s00637g PE=4 SV=1
A0A167F127_9ASCO58.21%2013e-86Sdt1p OS=Sugiyamaella lignohabitans GN=SDT1 PE=4 SV=1
UniRef50_A0A167F12758.21%2019e-83Sdt1p n=68 Tax=saccharomyceta TaxID=716545 RepID=A0A167F127_9ASCO
Q6C090_YARLI54.63%2161e-80YALI0F26785p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F26785g PE=4 SV=1
A0A1E3PLD9_9ASCO52.61%2303e-78Pyrimidine 5-nucleotidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82888 PE=4 SV=1
A0A1E4TG04_9ASCO50.93%2161e-71Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_148023 PE=4 SV=1
SDT1_YEAST48.40%2193e-66Suppressor of disruption of TFIIS OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SDT1 PE=1 SV=1
Q5AK98_CANAL48.26%2013e-55Nucleotidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3922 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0041

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 368

Detailed signature matches

  1. Family IPR006439
    HAD hydrolase, subfamily IA
    1. TIGR01509
  2. Family IPR010237
    Pyrimidine 5-nucleotidase
    1. SFLDG01132 (C1.5.3:...)
    2. TIGR01993
  3. Domain IPR023214
    HAD-like domain
    1. SSF56784 (HAD-like)
    2. G3DSA:3.40.50...
    3. PF13419 (HAD_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Residue annotation

  1. SFLDG01132

Protein sequence

>MCA_05320_1
MINLFNHDVIFPQDEDEKPITLPTAKPLTIDTVVDNQEDDDRDVDDGRYVFFFDIDNCLYPKSTKIHELMKEYIHKYFVS
HLSLDDEEAQMLHSQYYRDYGLALEGLVRFHHIDALEYNKEVDDALPLDKILRPDNALRVMLSSIDRTKVRKLWLFTNAY
KSHGERVVKLLGIDDLFDGMTFCDYGEIPLVCKPKFEMFDKAMREAGVTRKDRCLYVDDSYLNVQAAMKYGWTAGSVLYV
ESEEELPKPLVGTHVIRSILDLPLIFPEIFSEDGMADFAHLICQPTYNLTIEELMKLAHMGEPKETKTINGVKKVIKAKG
EKSSSSDEELGTVTPATHEEKRSQWSRRLSKQLLDTELKKLKALESKN

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

None predicted.