Protein
MCA_05315_1
Length
580 amino acids
Gene name: ATG17
Description: Autophagy-related protein 17
Browser: contigD:989302-991129+
RNA-seq: read pairs 1119, FPKM 23.8, percentile rank 46.2% (100% = highest expression)
Protein function
| Annotation: | ATG17 | Autophagy-related protein 17 | |
|---|---|---|---|
| KEGG: | K08329 | ATG17 | autophagy-related protein 17 |
| EGGNOG: | 0PHBJ | ATG17 | Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity) |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05899_1 | 36.07% | 524 | 2e-89 | MIA_05899_1 |
| A0A0J9XHC2_GEOCN | 30.81% | 516 | 9e-63 | Similar to Saccharomyces cerevisiae YLR423C ATG17 Scaffold protein responsible for phagophore assembly site organization OS=Geotrichum candidum GN=BN980_GECA17s00087g PE=4 SV=1 |
| UniRef50_A0A0J9XHC2 | 30.81% | 516 | 2e-59 | Similar to Saccharomyces cerevisiae YLR423C ATG17 Scaffold protein responsible for phagophore assembly site organization n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHC2_GEOCN |
| A0A060T4M1_BLAAD | 28.91% | 512 | 2e-53 | ARAD1A18744p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A18744g PE=4 SV=1 |
| A0A1E3PP36_9ASCO | 26.80% | 515 | 2e-45 | APG17-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50592 PE=4 SV=1 |
| A0A167FF92_9ASCO | 26.39% | 538 | 2e-45 | Protein kinase regulatory subunit ATG17 OS=Sugiyamaella lignohabitans GN=ATG17 PE=4 SV=1 |
| ATG17_YARLI | 23.22% | 521 | 3e-19 | Autophagy-related protein 17 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ATG17 PE=3 SV=1 |
| A0A1E4TDG9_9ASCO | 25.81% | 279 | 2e-17 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58650 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1784
Protein family membership
- Autophagy-related protein 17 (IPR007240)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_05315_1 MAFPELKTWLEEAKESLSTAGPICNEANSLLSIARTKLENASVLWSQTKYLFESIKYQLRTLKTIRDELMQKQTRKTQQF EKLLKLLDNGEKELSEMLVKLEQCEIDPAIEADNRWREIRNQFSPQTSANEDLFQEWNKTQKALAEGEIKLRNLRSFVDE DSIIQLRENVSEKVKDMSMAIRQNEELIIQIQDVISRFSKDVSSYPQIPLTQHNKEATTGAGADSGNKQQQQQQSTISSS ITRKELEEAYDKTNEIAIHAHAMAMLLESLTHHYDQCCQALQMEKELTDMATTRNITNTEGRLNATPVTDEQLAVALDAK KEDLVDLMQVLENDSSELEVVVDELQERYADISTLSGQVSQYEETLMQAHQYAVSLFDRLEQFGSVMSLPQKKSPEQQQD LDTKSFPNNNLHTLLTMFQENQILISEATEEMETKLITEMENLKVYYRLFLQSYHKVLIEIDRRKTFQRGVEKYLSNIRS HLNYMLVEELKIREDFVQDISDFFPKDLWPGVLDPPPFFEIITNNMGDEFVIKEEDGGGGGDGDDENKEVKYGNLPNISP KNLQAAINEIKKSGLFIKDS
GO term prediction
Biological Process
GO:0006914 autophagy
Molecular Function
None predicted.
Cellular Component
None predicted.