Protein
MCA_05259_1
Length
905 amino acids
Gene name: SEC21
Description: Coatomer subunit gamma
Browser: contigD:786530-789248-
RNA-seq: read pairs 8871, FPKM 121.0, percentile rank 82.0% (100% = highest expression)
Protein function
| Annotation: | SEC21 | Coatomer subunit gamma | |
|---|---|---|---|
| KEGG: | K17267 | COPG | coatomer subunit gamma |
| EGGNOG: | 0PIB8 | SEC21 | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity) |
| SGD closest match: | S000005231 | SEC21 | Coatomer subunit gamma |
| CGD closest match: | CAL0000193121 | SEC21 | Coatomer subunit gamma |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X7E2_GEOCN | 65.50% | 913 | 0.0 | Coatomer subunit gamma OS=Geotrichum candidum GN=BN980_GECA05s00637g PE=3 SV=1 |
| MIA_00035_1 | 64.20% | 919 | 0.0 | MIA_00035_1 |
| A0A060T9K5_BLAAD | 61.52% | 907 | 0.0 | Coatomer subunit gamma OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C45474g PE=3 SV=1 |
| A0A167CGX1_9ASCO | 58.87% | 936 | 0.0 | Coatomer subunit gamma OS=Sugiyamaella lignohabitans GN=SEC21 PE=3 SV=1 |
| UniRef50_A0A167CGX1 | 58.87% | 936 | 0.0 | Coatomer subunit gamma n=5 Tax=Saccharomycetales TaxID=4892 RepID=A0A167CGX1_9ASCO |
| A0A1E3PFD5_9ASCO | 54.74% | 908 | 0.0 | Coatomer subunit gamma OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48009 PE=3 SV=1 |
| Q6C314_YARLI | 50.54% | 928 | 0.0 | Coatomer subunit gamma OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F03454g PE=3 SV=1 |
| A0A1E4TDY5_9ASCO | 48.59% | 920 | 0.0 | Coatomer subunit gamma OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_97844 PE=3 SV=1 |
| A0A1D8PDE3_CANAL | 43.27% | 943 | 0.0 | Coatomer subunit gamma OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SEC21 PE=3 SV=1 |
| COPG_YEAST | 41.59% | 928 | 0.0 | Coatomer subunit gamma OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC21 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0114
Protein family membership
- Coatomer gamma subunit (IPR017106)
Domains and repeats
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Domain
-
Domain
1
100
200
300
400
500
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700
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905
Detailed signature matches
no IPR
Unintegrated signatures
Protein sequence
>MCA_05259_1 MSALNYKKNDDIDSGSLDKMTVFQECISGFNASPISSKRCRALLTKLIHLINLGEVFPPEEATSLFFSITKLFQHKDPAL RQMVYVAIKDLSSTANDVIMVTSSIMKDIQSSSDAIYKPNAIRALIRIIDSSTVPSIERLMKTAITDKNPIVVAAALVSS YHLVPIAKDVVRRWASETQETLLQHPSKSKPGMMNSLMSHSPTMYEYHAIGLLYELRNHDKMALMRIIHMLTNSSAPPLN WAAASFVVRLIAKLIEEDESTAEQLLPSLRQLLKHNSDIVTLEAVKCIMQLKAADAAAINDALGVIQLFLQTPRTASKFA AIRILNRYAMKHPQEASICNLELENLISDNSRAIATYAITTLLKTGKENSVDRLMSQISGFMNEISDEFKIIVIDAIRSL ALKFPSKYQRMLSFLAGGLRDDGGIQYKTAVVEALFDMIRYIPASKEAALGHLSELVEDCEFSELSVRILHLLGSEGPST SQPTKYIRYIYNRVVLENAVIRAAAVTALSKFALVDDPSVRKSVKVLLTRCLNDVTDEVRDRAALALRFIDLSQEEAVEY LAPKTIYSFPQMEQELTKYLSAGDKSVFLKPFDITIIARVTEEQARAQALELRTKAISTDSGESAADIKRAEEKKSAERE LLQDKTKEYAAALSAIPEFESYGQILKSSEPVALTESEMEYVVTAVKHLFKDHLVIQYNVTNTFNEYVLENVLVELQGAF DEEFVIPIEKLVPDSTETIYVSMARPEDYVVDSIYNNLKFVSKEIDPNTNEPVEEGYEDEYNLENLDITIGDYLIPAFIG NFSHQWDSLGEHESGATYDLGTEMKLSETVDYIIKLLSLMPLEGSDVVTSTASHVLKLFGRTIMGAKVAVQARMVYSSKK GVTMLLKARSEDETVAALVSEALGS
GO term prediction
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Molecular Function
GO:0005198 structural molecule activity
GO:0005488 binding
Cellular Component
GO:0030117 membrane coat
GO:0030126 COPI vesicle coat