Protein

MCA_05170_1

Length
540 amino acids

Gene name: PFA3

Description: Palmitoyltransferase PFA3; required for vacuolar membrane fusion

Browser: contigD:526155-527956+

RNA-seq: read pairs 1891, FPKM 43.2, percentile rank 62.2% (100% = highest expression)

Protein function

Annotation:PFA3Palmitoyltransferase PFA3; required for vacuolar membrane fusion
KEGG:K20028ZDHHC2_15_20 palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
EGGNOG:0PH9GPFA3Palmitoyltransferase specific for VAC8. Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization
SGD closest match:S000005270PFA3Palmitoyltransferase PFA3
CGD closest match:CAL0000175769PFA3Palmitoyltransferase PFA3

Protein alignments

%idAln lengthE-value
A0A060T1V5_BLAAD51.75%3153e-111Palmitoyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C27368g PE=3 SV=1
UniRef50_A0A060T1V551.75%3156e-108Palmitoyltransferase n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T1V5_BLAAD
A0A0J9XK99_GEOCN51.62%3391e-110Palmitoyltransferase OS=Geotrichum candidum GN=BN980_GECA32s02353g PE=3 SV=1
MIA_03117_143.68%3808e-104MIA_03117_1
A0A1E4TLG0_9ASCO38.01%3214e-69Palmitoyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147618 PE=3 SV=1
PFA3_YARLI36.64%3333e-64Palmitoyltransferase PFA3 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PFA3 PE=3 SV=1
A0A1E3PDY3_9ASCO35.63%3349e-56Palmitoyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28143 PE=3 SV=1
PFA3_CANAL34.78%3455e-49Palmitoyltransferase PFA3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PFA3 PE=3 SV=2
PFA3_YEAST34.36%2912e-41Palmitoyltransferase PFA3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PFA3 PE=1 SV=1
A0A161HKX3_9ASCO52.94%852e-23Putative palmitoyltransferase ZDHHC20 OS=Sugiyamaella lignohabitans GN=AWJ20_804 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9271

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 540

Detailed signature matches

  1. Domain IPR001594
    Palmitoyltransferase, DHHC domain
    1. PF01529 (DHHC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. PS50216 (DHHC)
  4. SIGNAL_PEPTIDE (Sig...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. TMhelix
  9. TRANSMEMBRANE (Tran...)
  10. mobidb-lite (disord...)

Protein sequence

>MCA_05170_1
MAIVRRLCLLCQITCCTIASWFPRIGLNIVMLWGFYTHIFKICNVVFSNSPIIRNTLTFFTAVFYALSFIAYGETILVGA
GSPLDIPGFPVRPTDLENGVESTPPHVELNVTAKDNGMMRYCNKCQCWKPDRTHHCSSCRKCILRMDHHCPWFATCIGFR
NQKFFLLFLFYVSLFCITCCIGSVYAIANFIYRLPDLEKNPVVAASLDRESVYLPLSWIALGIVSTVMGLAVSLFAAYSI
YLAVKNETVLESLEAVRYKTSLAPSSYRYREAPTSKSIGNIFDIGWKKNLRQIMGDKVWEWFIPFKQNTVGDGTWFPINQ
ELYRQAQEQAEIEHMSLQQQYNYRKQQRNLMRQEVASEANISVYSNGNDIHTHYRASEPSYEMNSLQTNNSAGSTDRYSN
NFNPGNKESSQKFVSSPGQMHNQPNNNINNNNGHINTTTTITHDPSMMGAILNGNGVSSIGMRSTSSNRYKPSFNGFNQH
ESLSRSISPSLASLSGTTDKYSDYNQRPSSNLDDIDDLDYISNPKKVEKIPLTYLNHSID

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.