Protein
MCA_05163_1
Length
568 amino acids
Gene name: PTC6
Description: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial
Browser: contigD:503358-505065+
RNA-seq: read pairs 1352, FPKM 29.4, percentile rank 52.2% (100% = highest expression)
Protein function
| Annotation: | PTC6 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial | |
|---|---|---|---|
| KEGG: | K19708 | PTC6 | protein phosphatase PTC6 [EC:3.1.3.16 3.1.3.43] |
| EGGNOG: | 0PFGC | PGUG_03646 | phosphatase 2C |
| SGD closest match: | S000002133 | PTC6 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial |
| CGD closest match: | CAL0000190127 | PTC6 | Type 2C protein phosphatase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04787_1 | 70.09% | 438 | 0.0 | MIA_04787_1 |
| A0A0J9X989_GEOCN | 58.64% | 428 | 0.0 | Similar to Saccharomyces cerevisiae YCR079W PTC6 Mitochondrial type 2C protein phosphatase (PP2C) with similarity to mammalian PP1Ks OS=Geotrichum candidum GN=BN980_GECA06s03618g PE=4 SV=1 |
| A0A167C226_9ASCO | 52.82% | 443 | 1e-158 | Type 2C protein phosphatase PTC6 OS=Sugiyamaella lignohabitans GN=PTC6 PE=4 SV=1 |
| UniRef50_A0A167C226 | 52.82% | 443 | 4e-155 | Type 2C protein phosphatase PTC6 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167C226_9ASCO |
| A0A060T7S9_BLAAD | 49.77% | 438 | 2e-142 | ARAD1C30052p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C30052g PE=4 SV=1 |
| A0A1E3PRB6_9ASCO | 52.14% | 420 | 4e-138 | Protein serine/threonine phosphatase 2C (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5978 PE=3 SV=1 |
| Q6CDN3_YARLI | 51.42% | 424 | 1e-132 | YALI0B22616p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B22616g PE=4 SV=1 |
| A0A1E4TET5_9ASCO | 45.54% | 415 | 5e-116 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31235 PE=4 SV=1 |
| Q59MW1_CANAL | 40.60% | 436 | 6e-102 | Type 2C protein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PTC6 PE=4 SV=1 |
| PDP2_YEAST | 32.40% | 466 | 1e-60 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PTC6 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9381
Predicted cleavage: 142
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
568
Detailed signature matches
no IPR
Unintegrated signatures
-
cd00143 (PP2Cc)
-
mobidb-lite (disord...)
Residue annotation
-
Active site cd00143
Protein sequence
>MCA_05163_1 MIQLQTNRIGLYSNTSKAFTSLLKSHSSLKNTTYSTATLTHLPYQYRNHHTNSHHLNVTATNFNSGTPQRPVLTSNKHNN YPSSASSSLSSPFSLSLKTPFQFPYTPLTHIRKQHQSSQHSQHSSSSLSTPPQPQQQQLRNVSSFYTWEMQQGSKTVKAR ISLLKSPGYIGHYTSRMNRPYNEDRYFAGVLQLPTGSSLRPMSSRYKTLEEEYDYDDNDLTSPHLTRKENLRPVFNFAVF DGHGGQECSQFLQENLARYVESCDLTSSDRLADQYKTVIGGYWKRWRNGFSKYMAKMRAIDDFQIRLPIAFLQADFDYMQ QYSKAGSTCTSIYLYTDDEYSAPVGRHQVLTPGAFWEQGQSVQLVVAHVGDTRCIICDSLGEAHPLTSNHHPSSPIESMR LQRYASSFMTDSFGESRFLGSFANTRSFGDFAGKARGITAEPDILEHEVGTPSGKFPVSNKKTHLTGGHASGNEAFIVLV SDGVSGMMSDQEIVDIIITTADRGGSLRGTPQLAAEEVVKYAEILGGDDNATCMVIRLGGWNQWPTNSDRTAELRENRMK TAFDNRRQ
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0003824 catalytic activity
Cellular Component
None predicted.