Protein

MCA_05157_1

Length
264 amino acids

Gene name: EMG1

Description: Ribosomal RNA small subunit methyltransferase NEP1

Browser: contigD:493514-494309+

RNA-seq: read pairs 1510, FPKM 70.4, percentile rank 72.8% (100% = highest expression)

Protein function

Annotation:EMG1Ribosomal RNA small subunit methyltransferase NEP1
KEGG:K14568EMG1 rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260]
EGGNOG:0PGWKFG09853.1Nucleolar essential protein 1
SGD closest match:S000004176EMG1Ribosomal RNA small subunit methyltransferase NEP1

Protein alignments

%idAln lengthE-value
MIA_04808_189.02%2644e-177MIA_04808_1
A0A0J9XCX0_GEOCN86.07%2444e-157Similar to Saccharomyces cerevisiae YLR186W EMG1 Member of the alpha/beta knot fold methyltransferase superfamily OS=Geotrichum candidum GN=BN980_GECA10s03695g PE=4 SV=1
A0A167DQ59_9ASCO80.72%2491e-148Emg1p OS=Sugiyamaella lignohabitans GN=EMG1 PE=4 SV=1
UniRef50_C4Y1R780.79%2295e-137Nucleolar essential protein 1 n=7 Tax=saccharomyceta TaxID=716545 RepID=C4Y1R7_CLAL4
Q6C7E4_YARLI74.05%2622e-141YALI0E01496p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E01496g PE=4 SV=1
A0A1E3PRH8_9ASCO81.22%2291e-140Nucleolar essential protein 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48685 PE=4 SV=1
A0A060SWZ1_BLAAD76.52%2471e-140ARAD1A09328p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A09328g PE=4 SV=1
NEP1_YEAST79.50%2392e-139Ribosomal RNA small subunit methyltransferase NEP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EMG1 PE=1 SV=1
A0A1D8PF50_CANAL75.70%2512e-13918S rRNA pseudouridine methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NEP1 PE=4 SV=1
A0A1E4TCB8_9ASCO72.47%2471e-132Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_139405 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0036
Predicted cleavage: 64

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 264

Detailed signature matches

  1. Family IPR005304
    Ribosomal biogenesis, methyltransferase, EMG1/NEP1
    1. PF03587 (EMG1)
  2. Domain IPR029028
    Alpha/beta knot methyltransferases
    1. SSF75217 (alpha/bet...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_05157_1
MVSKDPVPFKPGHYSNSSDSKQRTSYIGKVKQENINLVPQAPKVLSSKDKSTQRLIVVLSNACLESIKVSGYDGDRYALL
NCDDHQGILKRTKRDIADARPDITHQCLLTLLDSPINKAGKLQVYIETTRGVLIEVNPTVRIPRTFKRFSGLMVQLLHKL
SIRSVNSEERLLKVIKNPITDHLPSKCRKVTLSFDAPIQSVQSYVKTLDEDESICVFVGAMARGKDTFADEYVDEKIGVS
NYSLSASVACSKFCHGCEDAWGIL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0008168 methyltransferase activity

Cellular Component

None predicted.