Protein
MCA_05140_1
Length
154 amino acids
Gene name: TIF11
Description: Eukaryotic translation initiation factor 1A
Browser: contigD:450234-450699-
RNA-seq: read pairs 3864, FPKM 308.0, percentile rank 91.9% (100% = highest expression)
Protein function
| Annotation: | TIF11 | Eukaryotic translation initiation factor 1A | |
|---|---|---|---|
| KEGG: | K03236 | EIF1A | translation initiation factor 1A |
| EGGNOG: | 0PN1R | TIF11 | Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity) |
| SGD closest match: | S000004873 | TIF11 | Eukaryotic translation initiation factor 1A |
| CGD closest match: | CAL0000199255 | TIF11 | Tif11p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03043_1 | 87.85% | 107 | 9e-68 | MIA_03043_1 |
| A0A0J9X3I5_GEOCN | 83.18% | 107 | 3e-63 | Similar to Saccharomyces cerevisiae YMR260C TIF11 Translation initiation factor eIF1A OS=Geotrichum candidum GN=BN980_GECA02s04344g PE=3 SV=1 |
| A0A167FIK1_9ASCO | 80.29% | 137 | 2e-61 | Tif11p OS=Sugiyamaella lignohabitans GN=TIF11 PE=3 SV=1 |
| UniRef50_A0A167FIK1 | 80.29% | 137 | 6e-58 | Tif11p n=110 Tax=Eukaryota TaxID=2759 RepID=A0A167FIK1_9ASCO |
| A0A060T4Q5_BLAAD | 75.91% | 137 | 1e-60 | ARAD1C43010p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C43010g PE=3 SV=1 |
| Q5A5P8_CANAL | 75.96% | 104 | 1e-54 | Tif11p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TIF11 PE=3 SV=1 |
| IF1A_YEAST | 74.29% | 105 | 1e-53 | Eukaryotic translation initiation factor 1A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TIF11 PE=1 SV=1 |
| Q6C0W6_YARLI | 73.58% | 106 | 4e-53 | YALI0F21153p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F21153g PE=3 SV=2 |
| A0A1E3PIZ6_9ASCO | 72.90% | 107 | 2e-53 | Nucleic acid-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47024 PE=3 SV=1 |
| A0A1E4TBG1_9ASCO | 68.27% | 104 | 6e-50 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_27922 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0587
Predicted cleavage: 14
Protein family membership
- Translation initiation factor 1A (eIF-1A) (IPR001253)
Domains and repeats
-
Domain
1
20
40
60
80
100
120
140
154
Detailed signature matches
no IPR
Unintegrated signatures
-
-
mobidb-lite (disord...)
Residue annotation
-
RNA binding site c...
Protein sequence
>MCA_05140_1 MAKNKGKGGKNRRRGKNDNESFKRELVIKEEGQEYAQVTKMLGNGRIETSCFDGVKRIGHIRGKMRKKVWINQGDIILVS LREFQDEQCDVIVKYTPDEARTLKAQGELPESARINEGDPYGQGSDEECNFEFDNNDDSDEEDEEEGKLDIDDI
GO term prediction
Biological Process
GO:0006413 translational initiation
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Cellular Component
None predicted.