Protein

MCA_05122_1

Length
978 amino acids

Gene name: RPN2

Description: 26S proteasome regulatory subunit RPN2

Browser: contigD:406992-409929+

RNA-seq: read pairs 11706, FPKM 147.7, percentile rank 84.7% (100% = highest expression)

Protein function

Annotation:RPN226S proteasome regulatory subunit RPN2
KEGG:K03032PSMD1 26S proteasome regulatory subunit N2
EGGNOG:0PGI2RPN226S proteasome regulatory subunit
SGD closest match:S000001337RPN226S proteasome regulatory subunit RPN2
CGD closest match:CAL0000182505RPN2Proteasome regulatory particle base subunit

Protein alignments

%idAln lengthE-value
MIA_03826_178.11%9500.0MIA_03826_1
A0A0J9XHY8_GEOCN71.17%9540.0Similar to Saccharomyces cerevisiae YIL075C RPN2 Subunit of the 26S proteasome OS=Geotrichum candidum GN=BN980_GECA18s01407g PE=4 SV=1
A0A060SYE9_BLAAD62.30%9760.0ARAD1C00616p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C00616g PE=4 SV=1
A0A167FVY7_9ASCO60.39%9720.0Proteasome regulatory particle base subunit RPN2 OS=Sugiyamaella lignohabitans GN=RPN2 PE=4 SV=1
A0A1E3PSI2_9ASCO59.94%9760.026S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44529 PE=4 SV=1
Q6C288_YARLI58.54%9600.0YALI0F09834p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F09834g PE=4 SV=1
UniRef50_Q6C28858.54%9600.0YALI0F09834p n=10 Tax=Saccharomycetales TaxID=4892 RepID=Q6C288_YARLI
Q5A3L0_CANAL56.59%9560.0Proteasome regulatory particle base subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPN2 PE=4 SV=1
RPN2_YEAST53.38%7980.026S proteasome regulatory subunit RPN2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPN2 PE=1 SV=4
A0A1E4TGC5_9ASCO42.55%9870.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_24554 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0057

Protein family membership

Domains and repeats

  1. Domain
  2. Repeat
1 100 200 300 400 500 600 700 800 900 978

Detailed signature matches

  1. Family IPR016642
    26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit
    1. PIRSF015947 (26S_pr...)
  2. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  3. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
  4. Repeat IPR002015
    Proteasome/cyclosome repeat
    1. PF01851 (PC_rep)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. PF13646 (HEAT_2)
  3. mobidb-lite (disord...)

Protein sequence

>MCA_05122_1
MALVSAAPVLALLEEPDYHLKEYALKSLDENVPQLWAEIANNISQIEELYEDPKFPSQKLAALVASKVYYNLGEFDTSMK
YALLAGDKFDLTQKSEYIETIVSKCIDHYIFLSQKLLEENEDPVDAAQAIKSIDPALTQIVERMLKRCVDDGEFNLAIGV
ALDARRLDFVESIIKSNLKNQDEALELINYVLDCSINIVNVREFRNNVLRTLVPLIKGLDSPDYFAISKIIVQLNEATIA
IDLFNDLLENTKNENNVMVAYQVAFDLVASASQELLEKVHSSFVKTKESEEFTKLTKILSGIPTCDYNLTFLKKHNNTDI
NILNKTKSLMDGRSSIFHNAVTFENAFLHAGTTSDSFVRNNLEWLGRATNWTKFTATAALGVIHQGNLTQARRILQPYFP
GNTPSSCYTQGGSLYALGIIFAGHGREVLDYLLTQLVEGSGIQGHEDEVVLHGASLGLGVAGMGSGNIDVYEKLRTILYY
DSAIAGEGAGLAMGLVMLGSASEIAVSEMLQYAQDTQHEKIIRSLAMGLALLMYGKEEEADSLIEQLITEQNPILRYGGA
FTIALAYAGTGNNKAIKRLLHIAVSDASDDVRRASVISLGFILLRNYTVVPRMVELLSESHNPHVRYGTALALGISCAGT
GLKDAVDVLEPMTKDPVDFVRQGALIAIAMILIQQNERTYPGLKAFNETFASVIQNKHEDAVAKFGAALAQGIIDAGGRN
VTISLQHNQMGNLNMKAVVGLAVFTQYWYWFPLTHFLSLSFTPTTIVGVKEDLYVPDFDFVSSAKPKLFAYPPKIEEASE
TKPEKLETAILSTTNRVRTRAKKLSKAKEKKEAVDSKKPTIKTETDDKMEIDEEKRDSSVIAATPASTTASTSEGSKETI
EKVPTKSGRKYNKVENMSRVVPAQLKYISFEENSRYVPVRKLRGSGGVVIVKDLKPDEPAEMIVTVRQKAEEESGEAPLP
RPFTYESDGESNEDEEEN

GO term prediction

Biological Process

GO:0042176 regulation of protein catabolic process

Molecular Function

GO:0005488 binding
GO:0030234 enzyme regulator activity

Cellular Component

GO:0000502 proteasome complex