Protein
MCA_05112_1
Length
353 amino acids
Gene name: OMA1
Description: Mitochondrial metalloendopeptidase OMA1
Browser: contigD:384464-385526-
RNA-seq: read pairs 1669, FPKM 58.3, percentile rank 68.6% (100% = highest expression)
Protein function
| Annotation: | OMA1 | Mitochondrial metalloendopeptidase OMA1 | |
|---|---|---|---|
| EGGNOG: | 0PKTX | FG10192.1 | mitochondrial inner membrane |
| SGD closest match: | S000001795 | OMA1 | Mitochondrial metalloendopeptidase OMA1 |
| CGD closest match: | CAL0000185639 | OMA1 | Metalloendopeptidase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03834_1 | 58.77% | 308 | 6e-130 | MIA_03834_1 |
| A0A0J9XA08_GEOCN | 52.13% | 305 | 6e-109 | Similar to Saccharomyces cerevisiae YKR087C OMA1 Metalloendopeptidase of the mitochondrial inner membrane OS=Geotrichum candidum GN=BN980_GECA07s02100g PE=3 SV=1 |
| A0A167FVT9_9ASCO | 49.42% | 342 | 3e-102 | Oma1p OS=Sugiyamaella lignohabitans GN=OMA1 PE=3 SV=1 |
| UniRef50_A0A167FVT9 | 49.42% | 342 | 8e-99 | Oma1p n=4 Tax=Saccharomycetales TaxID=4892 RepID=A0A167FVT9_9ASCO |
| A0A060T455_BLAAD | 45.93% | 307 | 1e-90 | ARAD1B00330p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B00330g PE=3 SV=1 |
| Q6C283_YARLI | 45.57% | 305 | 2e-80 | YALI0F09988p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F09988g PE=3 SV=1 |
| A0A1E3PQR7_9ASCO | 45.99% | 287 | 2e-77 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80949 PE=3 SV=1 |
| OMA1_YEAST | 42.81% | 278 | 1e-73 | Mitochondrial metalloendopeptidase OMA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OMA1 PE=1 SV=2 |
| Q5A663_CANAL | 37.38% | 313 | 3e-65 | Metalloendopeptidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=OMA1 PE=3 SV=1 |
| A0A1E4TKU9_9ASCO | 36.13% | 346 | 2e-57 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30535 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9999
Predicted cleavage: 71
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
300
353
Detailed signature matches
-
-
PF01435 (Peptidase_M48)
-
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
-
-
NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
-
cd07331 (M48C_Oma1_...)
Residue annotation
-
Zn binding site cd...
-
putative active si...
Protein sequence
>MCA_05112_1 MFQSTLRASSRSFISTTSLRTNCIVSRSLASPLGRVPLHVVRQQRTYATYNTFRGTTNGRRHIHDSRNLWERHWKLFTAF GVGFGIFIVSNLERTPISNRLRFMIVSPAMEDFVGEQGYQQVLAQYKRSLLPDLHPHTLRVKRVMKHLIKVSGLNENMDW RVHVIHDPTAPPNAFVLPSGKVFVFTSILPIAEDDDGLATVLSHETAHVLLRHSAESLSKAPFMILANLILLYMFNIRLD GLTSILFELPSSREHESEADYAGLIMMSRACYDPSQAAHFWERMGNFERKSAGPLSGAKIPELLSTHPATAHRIENMKKW LPDAEEEKARSGCYDNSHSFMEFSNLFKEPGLF
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004222 metalloendopeptidase activity
Cellular Component
None predicted.