Protein

MCA_05095_1

Length
321 amino acids

Gene name: RPN12

Description: 26S proteasome regulatory subunit RPN12

Browser: contigD:347173-348139-

RNA-seq: read pairs 5283, FPKM 202.7, percentile rank 88.3% (100% = highest expression)

Protein function

Annotation:RPN1226S proteasome regulatory subunit RPN12
KEGG:K03031PSMD8 26S proteasome regulatory subunit N12
EGGNOG:0PI8SRPN12proteasome regulatory
SGD closest match:S000001948RPN1226S proteasome regulatory subunit RPN12
CGD closest match:CAL0000184969orf19.213Proteasome regulatory particle lid subunit

Protein alignments

%idAln lengthE-value
MIA_04748_157.01%3353e-110MIA_04748_1
A0A0J9X6T9_GEOCN46.56%3202e-76Similar to Saccharomyces cerevisiae YFR052W RPN12 Subunit of the 19S regulatory particle of the 26S proteasome lid OS=Geotrichum candidum GN=BN980_GECA04s04707g PE=4 SV=1
A0A167E0H9_9ASCO43.93%3211e-72Proteasome regulatory particle lid subunit RPN12 OS=Sugiyamaella lignohabitans GN=RPN12 PE=4 SV=1
UniRef50_A0A167E0H943.93%3213e-69Proteasome regulatory particle lid subunit RPN12 n=4 Tax=Saccharomycetales TaxID=4892 RepID=A0A167E0H9_9ASCO
A0A060T0D0_BLAAD42.64%3266e-65ARAD1C12078p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C12078g PE=4 SV=1
A0A1E3PFX6_9ASCO42.12%2731e-56Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_43315 PE=4 SV=1
Q6CGK2_YARLI38.34%3136e-51YALI0A18612p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A18612g PE=4 SV=1
A0A1E4TDN8_9ASCO37.71%2369e-37Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_144519 PE=4 SV=1
RPN12_YEAST36.72%2567e-3326S proteasome regulatory subunit RPN12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPN12 PE=1 SV=3
Q59SD0_CANAL34.83%2678e-30Proteasome regulatory particle lid subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.213 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0227

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 321

Detailed signature matches

  1. Domain IPR033464
    CSN8/PSMD8/EIF3K
    1. PF10075 (CSN8_PSD8_...)
  2. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10

Protein sequence

>MCA_05095_1
MSLETLVQEYNSAFEQEQYSKVGQLLPRIKLELAKEGLLVPKTHASTQDLLKTRDILEKGILASIHLRNESEFVRLISEI
HPFFYSKNAHGVGLPKSENQYKIMALYLLLLLSQNQIAEFHTELETLDDLNSTLEGGQSNSSSASPLETDIYLRYPVLLE
QWLMEGSYHKVWKAITDPNQVPAREFGILAESLLFTVRDEIARSAEAAYDYLPMDNACHLLYLETVDELIKFAESQETGW
VVDKLGKKIIFPNLNEGPTAPSSIANSTNNSREELLLKNENVNDLKEDFDVTGEAIGNASSQPEAIIAQCLDYAREMETI
I

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.