Protein

MCA_05087_1

Length
377 amino acids

Gene name: OYE2D

Description: NADPH dehydrogenase 2; NADH flavin oxidoreductase NADH oxidase family protein

Browser: contigD:332617-333751-

RNA-seq: read pairs 971, FPKM 31.7, percentile rank 54.3% (100% = highest expression)

Protein function

Annotation:OYE2DNADPH dehydrogenase 2; NADH flavin oxidoreductase NADH oxidase family protein
KEGG:K00354E1.6.99.1 NADPH2 dehydrogenase [EC:1.6.99.1]
EGGNOG:0PGTGFG03210.1NADH flavin oxidoreductase NADH oxidase family protein
SGD closest match:S000001222OYE2NADPH dehydrogenase 2
CGD closest match:CAL0000196620OYE2NADPH dehydrogenase

Protein alignments

%idAln lengthE-value
A0A0J9XEE0_GEOCN53.49%3722e-135Similar to Saccharomyces cerevisiae YHR179W OYE2 Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) OS=Geotrichum candidum GN=BN980_GECA12s03805g PE=4 SV=1
A0A167DHV9_9ASCO53.12%3699e-131Oye2p OS=Sugiyamaella lignohabitans GN=OYE2 PE=4 SV=1
UniRef50_A0A0J9XIR149.87%3892e-125Similar to Saccharomyces cerevisiae YPL171C OYE3 Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIR1_GEOCN
A0A060TFD9_BLAAD50.00%3761e-124ARAD1D22418p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22418g PE=4 SV=1
Q6C4E1_YARLI49.87%3751e-119YALI0E27511p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E27511g PE=4 SV=1
OYE2_YEAST49.35%3835e-115NADPH dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OYE2 PE=1 SV=3
MIA_00225_147.11%3807e-115MIA_00225_1
A0A1E3PIH8_9ASCO46.32%3802e-113NADH:flavin oxidoreductase/NADH oxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46861 PE=4 SV=1
A0A1D8PPM0_CANAL43.48%3681e-88NADPH dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=OYE2 PE=4 SV=1
A0A1E4TKU7_9ASCO40.21%3832e-82Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22517 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6667
Predicted cleavage: 30

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 377

Detailed signature matches

  1. Domain IPR013785
    Aldolase-type TIM barrel
    1. G3DSA:3.20.20.70
  2. Domain IPR001155
    NADH:flavin oxidoreductase/NADH oxidase, N-terminal
    1. PF00724 (Oxidored_FMN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF51395 (FMN-linke...)
  2. cd02933 (OYE_like_FMN)

Residue annotation

  1. active site cd02933
  2. FMN binding site c...
  3. substrate binding ...
  4. catalytic residue ...

Protein sequence

>MCA_05087_1
MTKSNLFKPIKIGSLDLSHRLVMAPLTRFRSPNHIPSELQRIYYEQRSRTPGTFIITEATFISPKAGGLDNVPGIWNKDQ
INGWSKIIKDIHKNGSKVFMQLWALGREATPEVLEREGLPYVSSSANLIGYGGFEAGDKPRPLPKALTIPEIEEYIDDYV
KAAKNAIEAGADGVEIHMANGYLLEQFIWEGCNHRTDKYGGSIENRVRFPLQVLDSVVEAIGADKVGVRFSPWRFYTNND
GTTPIPTWSYLTEQIEKRAVAGKRIAYIHLIEPRGVLSSRPWMKYNEKGDNTIFNLLWSGPIINAGGYDLEKARKDADKY
DRWLIAVGRYFISTPDLVARWERGLPPNDYDRPTFYVGGEKGYIDYPFAEELESDKK

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.