Protein

MCA_05076_1

Length
591 amino acids

Gene name: DBF20A

Description: Serine/threonine protein kinase similar to Dbf20, in S. cerevisiae involved in late nuclear division

Browser: contigD:307793-309569+

RNA-seq: read pairs 1797, FPKM 37.5, percentile rank 58.9% (100% = highest expression)

Protein function

Annotation:DBF20ASerine/threonine protein kinase similar to Dbf20, in S. cerevisiae involved in late nuclear division
EGGNOG:0PI9EPGUG_04130serine threonine-protein kinase
SGD closest match:S000006315DBF20Serine/threonine-protein kinase DBF20
CGD closest match:CAL0000197161DBF2Cell cycle protein kinase DBF2

Protein alignments

%idAln lengthE-value
MIA_04811_187.01%4620.0MIA_04811_1
A0A0J9XAC7_GEOCN65.91%6190.0Similar to Saccharomyces cerevisiae YPR111W DBF20 Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins OS=Geotrichum candidum GN=BN980_GECA05s06973g PE=4 SV=1
Q6CEN9_YARLI73.36%5030.0YALI0B14201p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B14201g PE=4 SV=1
A0A060TDH0_BLAAD76.17%4700.0ARAD1D43824p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D43824g PE=4 SV=1
A0A1E3PL37_9ASCO76.15%4570.0Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51320 PE=4 SV=1
A0A167D789_9ASCO69.94%4690.0Serine/threonine-protein kinase DBF20 OS=Sugiyamaella lignohabitans GN=DBF20 PE=4 SV=1
UniRef50_A0A1E3NGY163.89%4680.0Uncharacterized protein n=2 Tax=Pichiaceae TaxID=1156497 RepID=A0A1E3NGY1_9ASCO
A0A1E4TAB4_9ASCO64.58%4800.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57814 PE=4 SV=1
DBF20_YEAST60.21%4703e-177Serine/threonine-protein kinase DBF20 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DBF20 PE=1 SV=2
DBF2_CANAL51.83%5461e-166Cell cycle protein kinase DBF2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DBF2 PE=2 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2303

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 591

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. Domain IPR000961
    AGC-kinase, C-terminal
    1. SM00133 (pkinase_C_6)
    2. PS51285 (AGC_KINASE...)
  4. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  5. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. cd05600 (STKc_Sid2p...)
  4. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd05600
  3. polypeptide substr...
  4. activation loop (A...
  5. hydrophobic motif ...

Protein sequence

>MCA_05076_1
MSKLNGFLAAIRSPNQQQQQQQHQHQHQQQQPQQVHQYDQVLDGVRDLQMGGVTLNAPPAALKQNLNQQSDKENVVMYTP
QQQQQLQQHPNVKEMSMEDYAKLNDPKIKRLVDVSQLYFFDYYFDLLTYVHSRQQRLARVKQTLEQIPDKQERHHQFVSY
LGRERVQLRKRRIKLKYHDFKILTQVGQGGYGQVYLAKKTDTKEVCALKVLNKKLLQKLDEVRHILTERDILTAAKSPWL
VKLLYAFQDPENVYLAMEFVPGGDYRTLLNNTGILNPRHTRFYISEMFCALNALHKLGYIHRDLKPENFLIDSSGHIKLT
DFGLASGAISKERVESMRIKLDALKDFEVPYRSVTERQKMYRSLRANVTNYAHSVVGSPDYMALEVLQGKKYDFTIDYWS
LGCMLFETLAGYPPFAGSTPDETYANLQRWRSTLRRPQYEDGRYVFSERTWDLITRLINYPRYRFQSFEEIQAHPYFAEV
NWDTLRESTPPFIPQLDSDTDAGYFDDFGNESDMAKYKEVMEKRSQVENLADKGGPLPSRAFIGFTFKHQKLQQNKNNSV
LEEIPPAGYRSGGQRSMRSRRQMENPFDTIF

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.