MCA_05057_1
Gene name: AGP2A
Description: General amino acid permease AGP2; Plasma membrane regulator of polyamine and carnitine transport
Browser: contigD:250628-252398+
RNA-seq: read pairs 2929, FPKM 61.3, percentile rank 69.8% (100% = highest expression)
Protein function
| Annotation: | AGP2A | General amino acid permease AGP2; Plasma membrane regulator of polyamine and carnitine transport | |
|---|---|---|---|
| KEGG: | K16261 | YAT | yeast amino acid transporter |
| EGGNOG: | 0QDKR | FG03985.1 | amino acid |
| SGD closest match: | S000000336 | AGP2 | General amino acid permease AGP2 |
| CGD closest match: | CAL0000191370 | AGP2 | Agp2p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02441_1 | 61.08% | 591 | 0.0 | MIA_02441_1 |
| A0A0J9X466_GEOCN | 63.72% | 554 | 0.0 | Similar to Saccharomyces cerevisiae YBR132C AGP2 High affinity polyamine permease OS=Geotrichum candidum GN=BN980_GECA01s07864g PE=4 SV=1 |
| Q6CCP6_YARLI | 57.31% | 581 | 0.0 | YALI0C07678p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C07678g PE=4 SV=1 |
| A0A167CUE2_9ASCO | 61.71% | 525 | 0.0 | Agp2p OS=Sugiyamaella lignohabitans GN=AGP2 PE=4 SV=1 |
| A0A1E3PS52_9ASCO | 61.20% | 500 | 0.0 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_19230 PE=4 SV=1 |
| A0A1E4TEZ2_9ASCO | 58.15% | 552 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31336 PE=4 SV=1 |
| UniRef50_A0A0D2EXM0 | 55.26% | 561 | 0.0 | Uncharacterized protein n=11 Tax=Dikarya TaxID=451864 RepID=A0A0D2EXM0_9EURO |
| AGP2_YEAST | 53.91% | 499 | 1e-161 | General amino acid permease AGP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AGP2 PE=1 SV=1 |
| Q5AMG7_CANAL | 46.27% | 549 | 4e-146 | Agp2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AGP2 PE=4 SV=1 |
| A0A060SX82_BLAAD | 37.43% | 569 | 7e-101 | ARAD1A02376p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A02376g PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1725
Protein family membership
- Amino acid/polyamine transporter I (IPR002293)
Domains and repeats
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Domain
Detailed signature matches
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PIRSF006060 (AA_tra...)
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PF00324 (AA_permease)
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PS00218 (AMINO_ACID...)
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no IPR
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_05057_1 MGILNRFSRNRNQNSGDLSTISIEQVDEKKQSVIQTSQYDSNLNKQSEALFADENGPTEEITYAQSDGTSLPSTDHTVRK LKPRHIQLIGIGGTIGTALFVAIGNTLRKAGPLGLLLAFISWCIVILCITNSCAEMVSYLPIPSPFISLSGRCVDDAFEV MAGWNFFIYEAILIPFEITAVNAILHFWIDGYSPGIPIAIQLVLYLLINIFAVQFYGESEYWLSIGKVILAVGLMFFTFI VMVGGNPQKDAFGFRYWKDPGVMNEYTQPGDWGRFLGFFAALSAAAYTIAGPEYVSMSAGEAQNPYKVMPKAFKAVFYRL TTFFILGALCVGILVPYNDPTLATAIDEGRPGAGASPYVIAMTNLNIKVLPHIVNFLILTACFSAGNSYTYCSSRTLYGL ALQGKAPKIFTICTKKGVPIFAVAVALAFGLLSFLQLSSKTNTVLNWMISLVTASQLINFCVICVTYYRFYRACLAQGID RKSFPYYGYFQPYCTYIGIFFPFIMIFLAGYPVFLDFDVATFLFSYIMVPICLFIYVGWKLWHKTPLKKYEEIDLYSGKE EIQRHLDTFIPPTPPTTWYGKFFNWLIGN
GO term prediction
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006810 transport
GO:0006865 amino acid transport
GO:0055085 transmembrane transport
Molecular Function
GO:0015171 amino acid transmembrane transporter activity
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane