Protein

MCA_05054_1

Length
1,773 amino acids


Browser: contigD:237733-243055+

RNA-seq: read pairs 2660, FPKM 18.5, percentile rank 39.4% (100% = highest expression)

Protein function

EGGNOG:0PH75rho guanyl nucleotide exchange factor
CGD closest match:CAL0000190069CDC24Rho family guanine nucleotide exchange factor

Protein alignments

%idAln lengthE-value
MIA_02439_140.32%3729e-80MIA_02439_1
A0A0J9X5Z7_GEOCN37.97%3744e-72Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA04s00747g PE=4 SV=1
UniRef50_A0A0J9X5Z737.97%3748e-69Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5Z7_GEOCN
A0A060T2I9_BLAAD35.57%3439e-60ARAD1C32560p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32560g PE=4 SV=1
Q6C1S9_YARLI41.43%2102e-42YALI0F13673p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13673g PE=4 SV=1
A0A167D1G0_9ASCO34.38%2241e-29Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_614 PE=4 SV=1
A0A1D8PNB5_CANAL25.14%1795e-08Rho family guanine nucleotide exchange factor OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC24 PE=4 SV=1
A0A1E4THH4_9ASCO28.36%2013e-07Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14730 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0651

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1600 1773

Detailed signature matches

    1. SSF48065 (DBL homol...)
    2. PF00621 (RhoGEF)
    3. PS50010 (DH_2)
    4. SM00325 (RhoGEF_3)
    1. SSF103657 (BAR/IMD ...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00160 (RhoGEF)
  2. mobidb-lite (disord...)

Residue annotation

  1. GTPase interaction...

Protein sequence

>MCA_05054_1
MTYSAAAIPSPINTVTANDYYHDSLAPARPQLVRKSRSTTFINTSANPTPTTATHPSFEDAEEIRSSLVAFDTSNPLATP
PMLTPKLQQDPSYTNYTKRRSHSFSSLSTDASNTTILTSSQNHDSIGSTIFTPTGSDFSINAADDDNELTAFSMRPASLT
NNPFRNSTGSSSSAKRTSTENPILPQTTSTPTADTTNIPEITTTTTTTTTTTTTPTTTSIPLEKSDTTVQSSEKESLFLS
SIYPHPPHSREPSSTPDLASNFLDHARVAPNNNSCQTLSQFPPSSRRPSNVNNVFSGSINTHSFSSLASFSSENSFKSYD
SNQSHISVKKRVERKLSIIPVKVPPNELNYPANDVSDANNQKRIRTKYNLIRELLSTEQTFAQDLEAILEVYYNQAKSYP
YKHFLYNGDVEVLFGTVEQILNASKDFVNNLKNFIPTYILHECNLSPSSNVELKDLESNVGILLLEYLPTMELAFKIYCT
QNEYQMNTLYRIQALASPTIDEWFAECKERSKGMTNAWTLDALLIKPVQRLLKYPLLYKSMLQTTPEYHPDYESIKCAYE
EVAKCATRINLEANTSKSTIARPSSRTSMGSTVSGSSTPAPPNSNTNAHTSFIPAPLVDENTLLERLKVDMHADRCLSEL
IEKFDARHLQFKKLISSIRGNTAFTQLHFDNARVLANSWYAFSCDQSEEVVVDSKYSKYKEFSEQFCSGASPLAHVITSN
MLSGNTNQNSALSRQQTSSSPSSSTSSLTPNNNNNNNNLNGSNPSISTTTSRTEAPQVPQSPVPPALAPAGLPVTPTTPV
SKKPVSPVSTARYRERVEKTVVAPLQQVLNICFTITETISMRNSLHTEFKRYIFTKNLEEDSKKSFFSNKSLAPTHTNSS
ISSTGSGSNSPSLDLSQAKSLMMKRTSNRLGQGNNTLSGIFHTGSFDFGDDSDSHSISGFSINSTHNSSSSQASKLTMRE
ITSKKADKFLLLHNSLKNDLPQFLKSSLEILEPCLQQLLNIQVEWLKSVVQTGDAEVYKFVPDRVPKNKDDFIIMNYLAS
CQAERKSFVAVSKLRIIQKDPEDSIGQQKKLSSSSSSIRSVKMSKRRSKSKPSLYESDLNDSSAPPPVPPVPQNLPTTSV
VPTTHSSEKQEGALIASSDSNTPTSAAPSRRQSTSSIIKGAPSDAPELPTDDVTMHSFRSSQESPKFRYSDSLEMGPLDD
PTETSFGSDTARSHRRAISDADSMDANSIHSFNRQTTSEDNDEKEDDDNNAMSPLSSPTETTQPLFPGDDDVTSVQQPFN
GSGGLSTISESPSSPSSSSVSSSPRKPRKSMTFSHKEDGHNHHQQHSRAASSSSTSSSSFSVTRPKSMTGLDMLQAQMMM
MSMHSGGNSNGNINTSILNRKAPPPPPLPDLSPTMSTISTFSSHSTGTTQTNVSSPPSSNRSSLKQEAVPVMSATAGKTE
NTVSSSQQQSHFKSMYKKRFKKHGIDASNVYLASSASSISSNDSNATISTYAPSDTTATQNASSTSLNTTPSISSKPHAT
NPPPPSTSSSSHSHSLTRGRSRKFGSASTSSGPAQTHHHISAPQNVTVRKCTNINEALKELEYQNLQFQQQLQQQQIQQL
QQQSGNNSTTTASSSSSSTHPLAQVAPQQVAPSNNQSSITRRFSISSITSLTSVGSSASTSRRLSAISMRSAGGTGDSAS
VHSSNSSSSLSSSSNSSSVPQSPQQPQMSPPPIPQLPQQQQQQQQQQHSKNKFRSTLMALKTGLKSSSSGNSSLPSPNTS
PNSPGMYNRRSMM

GO term prediction

Biological Process

GO:0035023 regulation of Rho protein signal transduction

Molecular Function

GO:0005089 Rho guanyl-nucleotide exchange factor activity

Cellular Component

None predicted.