Protein

MCA_05042_1

Length
506 amino acids

Gene name: ABD1

Description: mRNA cap guanine-N7 methyltransferase

Browser: contigD:205398-206919+

RNA-seq: read pairs 1166, FPKM 28.4, percentile rank 51.2% (100% = highest expression)

Protein function

Annotation:ABD1mRNA cap guanine-N7 methyltransferase
KEGG:K00565RNMT mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
EGGNOG:0PHZUABD1mRNA cap guanine-N7 methyltransferase
SGD closest match:S000000440ABD1mRNA cap guanine-N7 methyltransferase
CGD closest match:CAL0000182989ABD1mRNA cap guanine-N7 methyltransferase

Protein alignments

%idAln lengthE-value
A0A060T7Q6_BLAAD46.01%4398e-132mRNA cap guanine-N7 methyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C23892g PE=3 SV=1
UniRef50_A0A060T7Q646.01%4392e-128mRNA cap guanine-N7 methyltransferase n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T7Q6_BLAAD
A0A0J9XFE1_GEOCN58.10%3273e-127Similar to Saccharomyces cerevisiae YBR236C ABD1 Methyltransferase OS=Geotrichum candidum GN=BN980_GECA13s01253g PE=4 SV=1
MIA_04838_156.51%3383e-126MIA_04838_1
A0A167EDM0_9ASCO48.90%3621e-113Abd1p OS=Sugiyamaella lignohabitans GN=ABD1 PE=4 SV=1
MCES_YARLI46.77%3875e-102mRNA cap guanine-N7 methyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ABD1 PE=3 SV=1
A0A1E3PL32_9ASCO42.92%4454e-102mRNA cap guanine-N7 methyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82589 PE=3 SV=1
MCES_CANAL43.98%3573e-82mRNA cap guanine-N7 methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ABD1 PE=3 SV=1
MCES_YEAST41.64%3537e-76mRNA cap guanine-N7 methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ABD1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0267

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 506

Detailed signature matches

  1. Family IPR016899
    mRNA (guanine-N(7))-methyltransferase
    1. PIRSF028762 (ABD1)
  2. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
  3. Domain IPR004971
    mRNA (guanine-N(7))-methyltransferase domain
    1. PF03291 (Pox_MCEL)
    2. PS51562 (RNA_CAP0_MT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd02440 (AdoMet_MTases)
  3. mobidb-lite (disord...)

Residue annotation

  1. S-adenosylmethioni...

Protein sequence

>MCA_05042_1
MYDPARDSWNGEKEETQESKPSQPKSPQEEEQQPSSKALEPVNEESANTVKEDKEPLENPSEISDPLEEKAQENKLSSPK
ETEVPSKTEEEPKSTNKKRPLTSNEDNYEPKNQEAEKNTAPESRDHFDQKQEENFNERSSSSHSENKPQSSSTQESNPAK
SPPRKRRLPNSRVSNEDRAKKTQQLRDRIERNERQNDGDHYNNNIRPRNDVEMVRSHYNQRPDQGHEGRQRSPIIKLRSF
NNWVKATLISMYCDRGYTVLDLGCGKGGDLTKWWKNRVSGYIGIDIADVSVKQARDRYDNSKAFRFWADFCVGDPFSQRV
DKIVAPGAFPVDIVSCQFCLHYSFESEDRARKLLENVSFALKSGHYFIGTIPNSDVFVKNIRRLGTETRRWGNKFYSVEF
VTDPPKDGIFDPPFGHKYNFFLEDAVGDVPEYVVPFEALIELAKDYGLELAYRKPFLKVFEQFANDEMAMSTARRMKVLK
DDGSPGIEGDEREIAAFYLAFAFRKI

GO term prediction

Biological Process

GO:0006370 7-methylguanosine mRNA capping

Molecular Function

GO:0004482 mRNA (guanine-N7-)-methyltransferase activity

Cellular Component

GO:0005634 nucleus