Protein
MCA_04977_1
Length
753 amino acids
Description: protein with Zn(2)C6 fungal-type DNA-binding domain
Browser: contigD:15737-17999-
RNA-seq: read pairs 2622, FPKM 43.0, percentile rank 62.0% (100% = highest expression)
Protein function
| Annotation: | protein with Zn(2)C6 fungal-type DNA-binding domain | ||
|---|---|---|---|
| EGGNOG: | 0PMIM | Fungal Zn(2)-Cys(6) binuclear cluster domain | |
| SGD closest match: | S000004218 | ECM22 | Sterol regulatory element-binding protein ECM22 |
| CGD closest match: | CAL0000183111 | ZCF21 | Zcf21p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04775_1 | 49.45% | 635 | 0.0 | MIA_04775_1 |
| A0A0J9XK14_GEOCN | 48.00% | 375 | 2e-107 | Similar to Saccharomyces cerevisiae YLR228C ECM22 Sterol regulatory element binding protein that regulates transcription of sterol biosynthetic genes OS=Geotrichum candidum GN=BN980_GECA21s00153g PE=4 SV=1 |
| UniRef50_A0A0J9XK14 | 48.00% | 375 | 3e-104 | Similar to Saccharomyces cerevisiae YLR228C ECM22 Sterol regulatory element binding protein that regulates transcription of sterol biosynthetic genes n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XK14_GEOCN |
| Q6CFP6_YARLI | 34.00% | 450 | 5e-67 | YALI0B05038p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B05038g PE=4 SV=1 |
| A0A167E381_9ASCO | 35.56% | 405 | 9e-67 | Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_1880 PE=4 SV=1 |
| A0A060T6P9_BLAAD | 33.60% | 372 | 1e-57 | ARAD1B17182p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B17182g PE=4 SV=1 |
| A0A1E3PK08_9ASCO | 30.47% | 384 | 6e-34 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51772 PE=4 SV=1 |
| A0A1D8PL89_CANAL | 38.74% | 111 | 9e-15 | Zcf21p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ZCF21 PE=4 SV=1 |
| A0A1E4TE67_9ASCO | 54.76% | 42 | 4e-10 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1799 PE=4 SV=1 |
| ECM22_YEAST | 52.50% | 40 | 1e-09 | Sterol regulatory element-binding protein ECM22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM22 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3879
Predicted cleavage: 14
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
753
Detailed signature matches
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Residue annotation
-
DNA binding site c...
-
Zn2+ binding site ...
Protein sequence
>MCA_04977_1 MARLNIKSSQSRTASDEQSARKIHLRRAHKKSHLGCQRCKERRIKCDEQFPICSQCKKAKFDCPYLFYTEAQKAEHIEKR NQAASASNLPINASNTSSGNKAIKPTICSEKDHPSLNSQQEQQPIKYSVNTVEASQPASIDNNYSDISSLPSQPSVPAQV TVTTSTSTAESPKFYAQNDYQLAMQQSRASTPTKNYHNSSGSNSPNSFTISFNGSHQPDSPRWPTSAVSPPSYSIFHKGM PIVERINQITDLQRRDLLGTVNLVRQGFETEIMRNAYSNWMSNTLALAFHHECLYHAVMAFSFGFQAVKTDLRHYRILSD KHRVIALTKFQSEIENVSPANTDALLGTSLILYWDAMYQVDTIYSYINMCRGLGAILEKVQINSSTTQAAICTTESLAQA IKSILYPRYSYAFFQELRSQIASLESYIQEDISNSGEEILREYEFLVYYTNKIANFLEMSGNYTYNSIYDPNILYSYLRE WITNFPCLAFSLDLLSSNASIVLYAYYDATSRALDAIFPEVRYLFQFSFIGPIDLVGIESAAFSVTRPDALEKLEYPLRL VSFFKKRTLTLSTLFIASDPLLMNSSGPLYRSRQPDLVLEKYVYSFKHPFDFQEHMPSFNPNVPNLMDASKPKPMSSTSN NGLGFGQLNTSLPPLFNGKNENNSNSDSSSQLPPPLPALSKLPSNSTPAQLPEDIDLRLPPLDKSGVDVDMSSSEKPPIL PPLSSLSMGCFKTYFDDRMDILEHFAPHQKDIC
GO term prediction
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Molecular Function
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0008270 zinc ion binding
Cellular Component
GO:0005634 nucleus