Protein

MCA_04959_1

Length
333 amino acids

Browser: contigC:4519577-4520916-

RNA-seq: read pairs 190, FPKM 7.0, percentile rank 20.6% (100% = highest expression)

Protein function

KEGG:K05925METTL3_14 mRNA (2'-O-methyladenosine-N6-)-methyltransferase [EC:2.1.1.62]
EGGNOG:0PIX2PGUG_03704MT-A70
SGD closest match:S000003160IME4N6-adenosine-methyltransferase IME4
CGD closest match:CAL0000194048orf19.1476mRNA (N6-adenosine)-methyltransferase

Protein alignments

%idAln lengthE-value
MIA_03126_165.79%3041e-146MIA_03126_1
A0A060T8V8_BLAAD47.35%3597e-105ARAD1C32758p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32758g PE=3 SV=1
Q6CFV0_YARLI43.45%3368e-94YALI0B03498p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B03498g PE=3 SV=1
UniRef50_Q6CFV043.45%3362e-90YALI0B03498p n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6CFV0_YARLI
IME4_YEAST52.65%2837e-92N6-adenosine-methyltransferase IME4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IME4 PE=1 SV=1
Q5ALV0_CANAL49.16%2999e-90mRNA (N6-adenosine)-methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1476 PE=3 SV=1
A0A167E8C0_9ASCO46.25%802e-17mRNA (N6-adenosine)-methyltransferase OS=Sugiyamaella lignohabitans GN=IME4 PE=4 SV=1
A0A0J9XK62_GEOCN25.17%1439e-07Similar to Saccharomyces cerevisiae YCL055W KAR4 Transcription factor required for gene regulation in response to pheromones OS=Geotrichum candidum GN=BN980_GECA21s01231g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2036

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 333

Detailed signature matches

  1. Family IPR007757
    MT-A70-like
    1. PF05063 (MT-A70)
    2. PS51143 (MT_A70)
  2. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
  3. SITE IPR002052
    DNA methylase, N-6 adenine-specific, conserved site
    1. PS00092 (N6_MTASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...

Protein sequence

>MCA_04959_1
MEIEKYIAESTSLRSVITSQFQNRDDKKYTPICFNTEQECPDKQKGSCNKIHFNAIIANNTDSSLGDCSYLNTCFKGKNC
RYVHYHISLPESLNHGITSSPKNSLSDSFSIPWTSLTFKPTSQISQFINFDIRQLDFSTLGKFAVVIADPPWDIHTNAIT
QSSTQSSAEATSDEAMMEFDMSSLQDEGIFFLWVTGRAIDIGRQCLKKWGYNHIEELIWCKTNQLGRTICTGRTGHWLNH
SKEHVLMGVKGAPAWGCKKVDIDLIVSATREKSHKPDELYEIAERMAGRHSRKLELFGGRRNLRPGWLTIGNQLGATEVA
EKDLINSISSISL

GO term prediction

Biological Process

GO:0006139 nucleobase-containing compound metabolic process
GO:0032259 methylation

Molecular Function

GO:0003676 nucleic acid binding
GO:0008168 methyltransferase activity

Cellular Component

None predicted.