Protein

MCA_04951_1

Length
702 amino acids

Gene name: MSD1

Description: Aspartate--tRNA ligase, mitochondrial

Browser: contigC:4502822-4504931+

RNA-seq: read pairs 1143, FPKM 20.1, percentile rank 41.5% (100% = highest expression)

Protein function

Annotation:MSD1Aspartate--tRNA ligase, mitochondrial
KEGG:K01876DARS aspartyl-tRNA synthetase [EC:6.1.1.12]
EGGNOG:0PG5RPGUG_00608Aspartyl-tRNA synthetase
SGD closest match:S000006025MSD1Aspartate--tRNA ligase, mitochondrial
CGD closest match:CAL0000199979orf19.4478Aspartate--tRNA ligase

Protein alignments

%idAln lengthE-value
MIA_04257_159.04%6910.0MIA_04257_1
A0A0J9X858_GEOCN54.93%6790.0Similar to Saccharomyces cerevisiae YPL104W MSD1 Mitochondrial aspartyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA05s01528g PE=3 SV=1
Q6C0A5_YARLI47.47%7120.0YALI0F26433p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F26433g PE=3 SV=1
UniRef50_Q6C0A547.47%7120.0YALI0F26433p n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6C0A5_YARLI
A0A1E3PIQ6_9ASCO49.41%6820.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_59808 PE=3 SV=1
A0A1D8PD81_CANAL44.88%7130.0Aspartate--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4478 PE=3 SV=1
A0A060TBK6_BLAAD43.21%7220.0ARAD1B08668p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B08668g PE=3 SV=1
SYDM_YEAST44.69%6870.0Aspartate--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSD1 PE=1 SV=1
A0A167ECQ3_9ASCO53.73%5100.0Aspartate--tRNA ligase MSD1 OS=Sugiyamaella lignohabitans GN=MSD1 PE=4 SV=1
A0A1E4TD05_9ASCO36.40%7066e-134Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4276 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9771
Predicted cleavage: 23

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 702

Detailed signature matches

  1. Family IPR002312
    Aspartyl/Asparaginyl-tRNA synthetase, class IIb
    1. PR01042 (TRNASYNTHASP)
  2. Family IPR004524
    Aspartate-tRNA ligase, type 1
    1. MF_00044 (Asp_tRNA_...)
    2. TIGR00459
  3. Domain IPR012340
    Nucleic acid-binding, OB-fold
    1. SSF50249 (Nucleic a...)
  4. Domain IPR006195
    Aminoacyl-tRNA synthetase, class II
    1. PS50862 (AA_TRNA_LI...)
  5. Domain IPR004364
    Aminoacyl-tRNA synthetase, class II (D/K/N)
    1. PF00152 (tRNA-synt_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.50...
  2. G3DSA:3.30.93...
  3. SSF55681 (Class II ...)

Protein sequence

>MCA_04951_1
MFFVKTSLLKQINRTPLARVRWNSTLPDITSTLSKFEFPRSTSSIKHLEEQKRDFDSLITCNGWIDRKPKKLGKALVFGS
LRDINGDTIQLVDSNVPSLIRSLKQESAVSITGKLKERHSVDGKNKSWDLTVEKAVTLNEANDVGSQLFTGNTKEWPQQY
RYLQLRSPYFQKIIKSRSHIMKTCRKVLDDLEFTEVDTPLLFKSTPEGAREFLIPTRKNGLMYALPQSPQQYKQLLMASG
IHKYYQIAKCFRDEDLRQDRQPEFTQLDMEMSFSNGEDVRNVIEKVIKAVWKDNCQPIKVSDVETRSPVLYTLNPEDNFE
SLIPITPDNMGKDLHFTSITYNEAISRFGIDKPDVRSSFEIIDLQKCGVAKATENEAFTVFEVMVIPNALSLNNSVKNVQ
KDVTNELIQKITDKNNYKSRIPNVVVIRDQKTLDTWTDEFSGMAQFTVGTKELNKILNLKIGDIIAGSTRAAINYENPTP
LGKLRSLAIESTLPHGLYSRKISHTCSANTQISNSVESDFAVMWVVDFPLFNPVEVEQELVRDSKIEQDAKALYPKFDYN
KYVSTHHPFTMCNVSDYELLDQSPLSVRGQHYDLVMNGVELGGGSTRIHDTELQKFIFEKILKIKNYQILFGHLLKAFDT
GCPPHAGLAIGFDRMVAMLNNTDSIRNVIAFPKSITGSDLMIGSPSKVTETQLRPYHIKCTK

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
GO:0016874 ligase activity

Cellular Component

None predicted.