Protein

MCA_04950_1

Length
309 amino acids


Gene name: RPN11

Description: Ubiquitin carboxyl-terminal hydrolase RPN11; Metalloprotease subunit of 19S regulatory particle

Browser: contigC:4501464-4502521-

RNA-seq: read pairs 7091, FPKM 282.6, percentile rank 91.4% (100% = highest expression)

Protein function

Annotation:RPN11Ubiquitin carboxyl-terminal hydrolase RPN11; Metalloprotease subunit of 19S regulatory particle
KEGG:K03030PSMD14 26S proteasome regulatory subunit N11
EGGNOG:0PHCZRPN1126S proteasome regulatory subunit
SGD closest match:S000001900RPN11Ubiquitin carboxyl-terminal hydrolase RPN11
CGD closest match:CAL0000177137orf19.7264Proteasome regulatory particle lid subunit

Protein alignments

%idAln lengthE-value
MIA_04256_185.29%3060.0MIA_04256_1
A0A0J9X9E3_GEOCN82.09%2962e-174Similar to Saccharomyces cerevisiae YFR004W RPN11 Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid OS=Geotrichum candidum GN=BN980_GECA05s01539g PE=4 SV=1
A0A167ECR4_9ASCO80.54%2981e-170Proteasome regulatory particle lid subunit RPN11 OS=Sugiyamaella lignohabitans GN=RPN11 PE=4 SV=1
A0A060TAQ2_BLAAD77.74%3011e-167ARAD1B08646p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B08646g PE=4 SV=1
Q6C0A6_YARLI78.87%2847e-163YALI0F26411p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F26411g PE=4 SV=1
A0A1E3PGZ6_9ASCO78.28%2902e-161Mov34-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47292 PE=4 SV=1
UniRef50_A0A0L0NS4472.37%3045e-152Uncharacterized protein n=14 Tax=Eukaryota TaxID=2759 RepID=A0A0L0NS44_9ASCO
A0A1D8PFZ8_CANAL74.48%2905e-153Proteasome regulatory particle lid subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7264 PE=4 SV=1
A0A1E4TG67_9ASCO71.08%2873e-147Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57200 PE=4 SV=1
RPN11_YEAST70.34%2901e-143Ubiquitin carboxyl-terminal hydrolase RPN11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPN11 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2125

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 309

Detailed signature matches

    1. SM00232 (pad1_6)
    2. PF01398 (JAB)
    1. PF13012 (MitMem_reg)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF102712 (JAB1/MPN...)
  2. cd08069 (MPN_RPN11_...)

Residue annotation

  1. MPN+ (JAMM) motif ...
  2. Zinc-binding site ...

Protein sequence

>MCA_04950_1
MNAFRSGMLPGMAGMDSLLDVAAVDNSETVYISSLALLKMLKHGRAGVPMEVMGLMLGTFVDEFTIHVVDVFAMPQSGTG
VSVEAVDEVFQTRMMDMLKQTGRDQIVVGWYHSHPGFGCWLSSVDIGTQQSFERLNKRSVAVVIDPIQSVRGKVVIDAFR
LTVPNQIALGNEPRQTTSNVGHLNKPAIQALIHGLNRHYYSININYKKTPLEEQMLLNLHKNPWASGLEIPDYQKHAEEN
HKSVEQMVKLAEQYTTRVKEEKELTEEQLKTRYVGKQDPKKHLEDTVTNRMEENIVSLLTTNVDKLSFK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.