Protein

MCA_04948_1

Length
512 amino acids

Browser: contigC:4498948-4500487+

RNA-seq: read pairs 710, FPKM 17.1, percentile rank 37.2% (100% = highest expression)

Protein function

KEGG:K12847USP39 U4/U6.U5 tri-snRNP-associated protein 2
EGGNOG:0PG9JFG06789.1U4 U6.U5 tri-snRNP-associated protein
SGD closest match:S000001901SAD1Pre-mRNA-splicing factor SAD1
CGD closest match:CAL0000187595orf19.7265mRNA splicing protein

Protein alignments

%idAln lengthE-value
MIA_05017_156.50%5310.0MIA_05017_1
A0A0J9X8C2_GEOCN55.70%4650.0Similar to Saccharomyces cerevisiae YFR005C SAD1 Conserved zinc-finger domain protein involved in pre-mRNA splicing OS=Geotrichum candidum GN=BN980_GECA05s02463g PE=4 SV=1
A0A1E3PHA2_9ASCO54.37%4583e-175Cysteine proteinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52416 PE=4 SV=1
UniRef50_I1RRQ447.62%5251e-163Uncharacterized protein n=37 Tax=Hypocreales TaxID=5125 RepID=I1RRQ4_GIBZE
A0A167ECY1_9ASCO45.35%5387e-142Sad1p OS=Sugiyamaella lignohabitans GN=SAD1 PE=4 SV=1
A0A060T5N9_BLAAD49.23%4573e-142ARAD1B08580p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B08580g PE=4 SV=1
Q6C622_YARLI46.51%4587e-141YALI0E13167p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E13167g PE=4 SV=1
A0A1E4TG57_9ASCO38.07%4572e-101Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_148073 PE=4 SV=1
SAD1_YEAST36.72%4632e-77Pre-mRNA-splicing factor SAD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAD1 PE=1 SV=1
A0A1D8PFY2_CANAL46.01%2131e-53mRNA splicing protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7265 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7106

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 512

Detailed signature matches

  1. Family IPR033809
    USP39
    1. cd02669 (Peptidase_...)
  2. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  3. Domain IPR001607
    Zinc finger, UBP-type
    1. SM00290 (Zf_UBP_1)
    2. PS50271 (ZF_UBP)
    3. PF02148 (zf-UBP)
  4. Domain IPR028889
    Ubiquitin specific protease domain
    1. PS50235 (USP_3)
  5. Domain IPR001394
    Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    1. PF00443 (UCH)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.90.70.10
  2. SSF54001 (Cysteine ...)
  3. SSF57850 (RING/U-box)
  4. mobidb-lite (disord...)

Residue annotation

  1. Active Site cd02669

Protein sequence

>MCA_04948_1
MTTKRTLRSEYDTPLSEQVNKKQKYDENAKTIVEADLSEDSSDSEYMVSRQEHGQTTDQSLYLETVNRSRLDFDFEKICS
VSLSNKNVYACLTCGKYFQGRGESSYAYFHSLDENHHVFINLNNLKIYILPEGYEVFSKALDDIKYVANPTYSKNEVSLL
DSPTCSPSFDLDHQQYTPGYIGINNIKQLNDYANVVIQLLTHVKPLRNFFLLKSFPATSPEIIKRTSVLFRKIWNPKAFK
AHVSPHDLLQYLSIISKRKFTSDTQSDPFDFLNWYMNKLHIGLGGSKSKPGTSIIQKIFQGSMVVKTRDLCDSDTSNKDS
ENTDKASVTSLPFMFLSLDLPPTPLFKSEDEQYTIPQVSLTSLLSKYDGNTEKEINGKSVKYELKTLPPYLIFHIKRFPK
TPTPGNKSNINSKVEDFGKQERNPTVVSFNHQSLDMQPYVHGQDSPMLYRLIANIIYESNLSTGGSKKHTWKIQLLNKST
DTWIQIQDLVVTPIMSQLLFLSESYIQVWEKL

GO term prediction

Biological Process

GO:0000245 spliceosomal complex assembly
GO:0006397 mRNA processing
GO:0016579 protein deubiquitination

Molecular Function

GO:0008270 zinc ion binding
GO:0036459 thiol-dependent ubiquitinyl hydrolase activity

Cellular Component

None predicted.