Protein

MCA_04932_1

Length
1,871 amino acids

Description: Putative GTPase activating protein (GAP) weakly similar to Bud2

Browser: contigC:4453123-4458891+

RNA-seq: read pairs 963, FPKM 6.4, percentile rank 19.6% (100% = highest expression)

Protein function

Annotation:Putative GTPase activating protein (GAP) weakly similar to Bud2
EGGNOG:0PJIUPGUG_05711GTPase Activating Protein
SGD closest match:S000001575BUD2Inhibitory regulator protein BUD2/CLA2
CGD closest match:CAL0000199838BUD2GTPase activating protein BUD2

Protein alignments

%idAln lengthE-value
MIA_00566_158.25%5150.0MIA_00566_1
A0A0J9X4V9_GEOCN35.85%7146e-118Similar to Saccharomyces cerevisiae YKL092C BUD2 GTPase activating factor for Rsr1p/Bud1p OS=Geotrichum candidum GN=BN980_GECA02s06406g PE=4 SV=1
UniRef50_A0A0J9X4V935.85%7141e-114Similar to Saccharomyces cerevisiae YKL092C BUD2 GTPase activating factor for Rsr1p/Bud1p n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X4V9_GEOCN
A0A161HG51_9ASCO34.49%6065e-94Bud2p OS=Sugiyamaella lignohabitans GN=BUD2 PE=4 SV=1
A0A060T9X2_BLAAD34.79%5957e-81ARAD1D22506p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22506g PE=4 SV=1
Q6C802_YARLI27.79%5834e-54YALI0D23903p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D23903g PE=4 SV=1
BUD2_YEAST27.90%5093e-41Inhibitory regulator protein BUD2/CLA2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BUD2 PE=1 SV=2
A0A1E4T9G8_9ASCO26.46%4612e-33Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_4531 PE=4 SV=1
BUD2_CANAL30.51%2951e-30GTPase activating protein BUD2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BUD2 PE=2 SV=1
A0A1E3PGX7_9ASCO32.44%2254e-26Rho GTPase activation protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83570 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1472

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1600 1871

Detailed signature matches

  1. Domain IPR001849
    Pleckstrin homology domain
    1. SM00233 (PH_update)
  2. Domain IPR000008
    C2 domain
    1. PS50004 (C2)
    2. SSF49562 (C2 domain...)
    3. G3DSA:2.60.40...
  3. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  4. Domain IPR001936
    Ras GTPase-activating protein
    1. PS50018 (RAS_GTPASE...)
    2. PF00616 (RasGAP)
    3. SM00323 (RasGAP_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.50...
  3. cd00030 (C2)
  4. mobidb-lite (disord...)

Protein sequence

>MCA_04932_1
MPESNTRSGVTNDKLSRLLKVPENSSPFKKSSSTSNIQSLNKSTISSPIPIESSISSLDDCSAVDSAEHPFINIKISTFD
DGHGDGNFMESHHLYNHPHLSRSDIVLSSEPISATTHHNDLQTSNSSSPQNSENSLFFELVHKPSDENRDNAVNKDQLKA
KSAVKTSANEPHKLSYPSSEWSTRYTRYAPIPKSPIASSPLLSSSSSSKIKILQLPKQLLTSSEKRNGSKAKSSSISEIN
APCTPGILNNSNFTSDQFRTSDSFQEINFNLNSSTSNTVHSISNIQEQTLVDSSSQSTSSLNNNLNPSFPSSNTFLNSET
QKSSTFDSSFIKQIHRKASRQSIINNTSYNKEMIASRDSQKILSPNQIYMDNQDLSYNNNNLTQMQSKNNQTSNSHENVK
AQAASISSDTPPKKTRSKRRFLSLHAKHKIKKHDNDTPSHFGTVASDPDSSMFVEKSNLSSSFPQKSTDYSLPSGLSYSL
SSKDIIPLYGNDSEIEDKGSDSESEKISDYEERSLQCKTYEHRILQFMKNNKGIIENKPIYFLNPATNTWEITSGSINLD
SRLTLISTSDNSQLLSQSIRSFEVRVDLESFVIFLSGLKKTDFFDSNCDSITLKVSTAQDNNDLEEWVAALMLHANLKPP
GLESKFFSPYMVKPGSRKVVISGSLKFLKATQDDFDSSRNDTPKIFTKFWVEGFATLYEDGTLEISSSPSSPTISTVQVG
SLSSSGIRCLDRSIFDTPNVIYLGKSLQNDDSFTSKVFSKLNRSTHVGNMPQSSSTYFHSNSSFSSPDFRVSTPTKSNSQ
IVNKRKSLQSFKQSSPHITEIEAKPIITLDENCFILNPHREDSDSFYIHFVSSSDCNRWFAALKSLARLEVFSPSTGDLS
QSFRISRTINIRIFEAKLDVSDFSLLTLDQQKKLQYPDTYVEIFIGNQICGRSTVAFSSRVPFWREDFTFKDLPGVSFPI
FYLVLRKKAVKGDLTPQMAVNCNQIDPVLGIVALSPEDIKKNGNVEKWYEIMPVFQPGCKNNFIDDLQFDWTQSKIRASL
CLKIAYEELTVGPSDCYKIIGRTLNALANNNWARLVQTDERRDVTNISETCLKISLSEPTGTAAINWLKSLITEEISKTH
KLMVEKSGDPNLFENSNTSFSDLKRNIDNTLFRGNSILTKSLERYMRIVGLDLLQDTVGKFVIMVLEAKPDLEMDPSRIK
LQLPKNAINASIDEIVKEHQQQLYEYASKMWHLIRDTAESIPYGFKEIFHHLAEELRTVLNQPQSSIYNSIAGFLFLRFF
CPGILNPKLFGLIKSQRINTSQRSLTLITKMIQCLANRTRFGIKEPWMIPMNSFFDVHEDELIEYFGKVINIDNISSSMI
NKHPIYFDYSPHQLAEYLNNPYVIDRTATFSRLIELWKTSYCTAEQLHKLTIQRNQTCKPGKKLIFEDLDKFEKEVIPTL
ENQPLEDLIIDFSKLCNYVDDVVRSIRAKLEVQQEAFNPENCEEYSRHIQLLSSPSKRQLFLGRMILSKNDFSTDLESVS
RVESESITLFSTTKPSSSPNLKEVELNKTDVDDSLDHDDALDYYYSESHEFDVSSPDYTHLKEGISSSDSQKSFSLSPNI
DLIKRPLSTQTFTSNQKHSQLASPTPVNKSKSKNRPRSFTFSPTTTSYSAVAAACTASKTNPIHLVPPIILSSSLNENQS
KSQSRAYTSLSNASMTSPSSSSVKTKDSRIRSKSQPRSGNLEDSKSSNKIPSRPSTPTVTSYSSFKIPQYFNHHPTHSST
KSLGHNRINRQHNRSRSSGYHSSIDGRTHLPGSVYLSNKSTYNSSRSVSNNYVTILPVYKSLPTDSSQNHSKINSQPTSS
TPTSLSFTSPVAAAAAAAAIAASNERKSPKI

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0043087 regulation of GTPase activity

Molecular Function

None predicted.

Cellular Component

None predicted.