Protein

MCA_04906_1

Length
416 amino acids

Gene name: PGK1

Description: Phosphoglycerate kinase

Browser: contigC:4385358-4386901+

RNA-seq: read pairs 81895, FPKM 2426.6, percentile rank 98.0% (100% = highest expression)

Protein function

Annotation:PGK1Phosphoglycerate kinase
KEGG:K00927PGK phosphoglycerate kinase [EC:2.7.2.3]
EGGNOG:0PGBUPGK1phosphoglycerate kinase
SGD closest match:S000000605PGK1Phosphoglycerate kinase
CGD closest match:CAL0000184891PGK1Phosphoglycerate kinase

Protein alignments

%idAln lengthE-value
MIA_05210_191.35%4160.0MIA_05210_1
A0A0J9X7B6_GEOCN85.54%4150.0Phosphoglycerate kinase OS=Geotrichum candidum GN=BN980_GECA05s00131g PE=3 SV=1
PGK_YARLI83.65%4160.0Phosphoglycerate kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PGK1 PE=3 SV=1
A0A060T070_BLAAD80.24%4150.0Phosphoglycerate kinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C05698g PE=3 SV=1
A0A1E4TL81_9ASCO79.28%4150.0Phosphoglycerate kinase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30657 PE=3 SV=1
A0A167E5X3_9ASCO79.86%4170.0Phosphoglycerate kinase OS=Sugiyamaella lignohabitans GN=PGK1 PE=3 SV=1
A0A1E3PDI2_9ASCO77.11%4150.0Phosphoglycerate kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_62893 PE=3 SV=1
PGK_CANAL74.28%4160.0Phosphoglycerate kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PGK1 PE=3 SV=1
UniRef50_A0A086ST5072.97%4180.0Phosphoglycerate kinase n=1 Tax=Acremonium chrysogenum (strain ATCC 11550 / CBS 779.69 / DSM 880 / JCM 23072 / IMI 49137) TaxID=857340 RepID=A0A086ST50_ACRC1
PGK_YEAST70.12%4150.0Phosphoglycerate kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PGK1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0329

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 416

Detailed signature matches

  1. Family IPR001576
    Phosphoglycerate kinase
    1. SSF53748 (Phosphogl...)
    2. PR00477 (PHGLYCKINASE)
    3. MF_00145 (Phosphogl...)
    4. PIRSF000724 (Pgk)
    5. PF00162 (PGK)
    6. cd00318 (Phosphogly...)
  2. Domain IPR015824
    Phosphoglycerate kinase, N-terminal
    1. G3DSA:3.40.50...
  3. SITE IPR015911
    Phosphoglycerate kinase, conserved site
    1. PS00111 (PGLYCERATE...)

Residue annotation

  1. substrate binding ...
  2. hinge regions cd00...
  3. ADP binding site c...
  4. catalytic site cd0...

Protein sequence

>MCA_04906_1
MSLQNKLSIKDLDLKDKKVFIRVDFNVPLDGTTITNNQRIVAALPSIKYAKEQGAKAIILASHLGRPNGEVNPKYSLKPV
AAELEKLLDTKVTFLPDCVGKETEEYVSKASNGEVILLENLRFHIEEEGSRKVDGKKEKADPAKVEEFRKSLTSLADVYV
NDAFGTCHRAHSSMVGVELPQRAAGFLVSKELTYFAKALEHPDRPFLAILGGAKVSDKIQLIDNLIPKVNTIIIGGGMAF
TFKKTLENVKIGNSLFDEDGSKIVGDLVKKAKENNVEIVLPVDYVTADKFSKDAQVGYATDSDGIPDGWQGLDVGEKSSE
LFSKAVANAKTILWNGPPGVFEFDNFSKGTKSLLDAVVKAVEGGATAIIGGGDTATVAKKFGAEDKLSHVSTGGGASLEL
LEGKDLPGVAALSSKA

GO term prediction

Biological Process

GO:0006096 glycolytic process

Molecular Function

GO:0004618 phosphoglycerate kinase activity

Cellular Component

None predicted.