Protein
MCA_04886_1
Length
480 amino acids
Browser: contigC:4342354-4343797+
RNA-seq: read pairs 2096, FPKM 53.8, percentile rank 66.9% (100% = highest expression)
Protein function
| KEGG: | K00931 | proB | glutamate 5-kinase [EC:2.7.2.11] |
|---|---|---|---|
| EGGNOG: | 0PFWT | FG06961.1 | glutamate 5-kinase |
| SGD closest match: | S000002708 | PRO1 | Glutamate 5-kinase |
| CGD closest match: | CAL0000178490 | PRO1 | Glutamate 5-kinase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00797_1 | 80.79% | 432 | 0.0 | MIA_00797_1 |
| A0A0J9XGP3_GEOCN | 70.77% | 455 | 0.0 | Similar to Saccharomyces cerevisiae YDR300C PRO1 Gamma-glutamyl kinase, catalyzes the first step in proline biosynthesis OS=Geotrichum candidum GN=BN980_GECA15s01451g PE=3 SV=1 |
| A0A1E3PFA9_9ASCO | 66.05% | 433 | 0.0 | Glutamate 5-kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47836 PE=3 SV=1 |
| A0A060TH21_BLAAD | 64.68% | 436 | 0.0 | ARAD1D35420p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D35420g PE=3 SV=1 |
| A0A167FGF0_9ASCO | 69.80% | 404 | 0.0 | Glutamate 5-kinase OS=Sugiyamaella lignohabitans GN=PRO1 PE=4 SV=1 |
| Q6CGH7_YARLI | 62.97% | 424 | 0.0 | YALI0A19206p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A19206g PE=3 SV=2 |
| A0A1E4TK56_9ASCO | 57.88% | 425 | 6e-178 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_21823 PE=3 SV=1 |
| PROB_YEAST | 58.80% | 432 | 1e-173 | Glutamate 5-kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRO1 PE=1 SV=2 |
| UniRef50_P32264 | 58.80% | 432 | 3e-170 | Glutamate 5-kinase n=174 Tax=saccharomyceta TaxID=716545 RepID=PROB_YEAST |
| A0A1D8PU95_CANAL | 59.07% | 430 | 4e-165 | Glutamate 5-kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRO1 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0005
Protein family membership
- Glutamate/acetylglutamate kinase (IPR001057)
- Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase (IPR005715)
- Glutamate 5-kinase (IPR011529)
- Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase (IPR005715)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
450
480
Detailed signature matches
no IPR
Unintegrated signatures
-
-
cd04242 (AAK_G5K_ProB)
-
mobidb-lite (disord...)
Residue annotation
-
nucleotide binding...
-
homotetrameric int...
-
putative phosphate...
-
putative allosteri...
Protein sequence
>MCA_04886_1 MVHHHSSHSHHGNGHHGHHGNHGHHGNHGSHLKTKQYTIVIKLGTSSLCHEETHEPRVANMALIVETVVRLRRDGHRVMI VSSGGIAVGLRQMKLPRRPKHLSAVQAIAAIGQARLIGQWDDMFRQFQQPIAQILLTRTDIADRAQYLNAANTMNELINM GVVPIVNENDTLSVHEIRFGDNDTLSAITAGMINADYLFLLTDVDCLYTDNPRVDPEAKPILVVDNITKLRVDVSTPGSN VGTGGMTTKLIAAELATSAGVTTIICKSSVPGNIHDIVKYIQCHDSPRLGPVNDVIDDIAKLELENNENVQKEIFESLMS ENVPLFTRFLPKRHPIKDREFWILHGLTAHGKIYIDRGAYRAITRSNKAGLLPVGIIKCEGHFHTNECVEIYAAKRLDSN PEEMDPEVEPILIGRALINYSDTEIDRIKGIQSCEIEKLLGYADSEYVAYRDSMAFYKGKRAHEILSTSEIKALERNITN
GO term prediction
Biological Process
GO:0006561 proline biosynthetic process
Molecular Function
GO:0003723 RNA binding
GO:0004349 glutamate 5-kinase activity
Cellular Component
GO:0005737 cytoplasm