Protein

MCA_04873_1

Length
673 amino acids


Gene name: ERT1B

Description: Transcription activator of gluconeogenesis ERT1

Browser: contigC:4302418-4304572+

RNA-seq: read pairs 131, FPKM 2.4, percentile rank 12.6% (100% = highest expression)

Protein function

Annotation:ERT1BTranscription activator of gluconeogenesis ERT1
EGGNOG:0PGKGERT1Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity)
SGD closest match:S000000443ERT1Transcription activator of gluconeogenesis ERT1
CGD closest match:CAL0000181843ZCF11Zcf11p

Protein alignments

%idAln lengthE-value
MIA_03429_159.00%4782e-160MIA_03429_1
A0A0J9XGC6_GEOCN60.50%4007e-139Similar to Saccharomyces cerevisiae YBR239C ERT1 Transcriptional regulator of nonfermentable carbon utilization OS=Geotrichum candidum GN=BN980_GECA15s01396g PE=4 SV=1
UniRef50_A0A0J9XGC660.50%4001e-135Similar to Saccharomyces cerevisiae YBR239C ERT1 Transcriptional regulator of nonfermentable carbon utilization n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XGC6_GEOCN
A0A060SXJ3_BLAAD48.73%3946e-115ARAD1A04158p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A04158g PE=4 SV=1
ERT12_YARLI46.75%4002e-106Transcription activator of gluconeogenesis ERT1-2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ERT1-2 PE=3 SV=1
A0A1E3PL84_9ASCO71.73%1913e-99Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50997 PE=4 SV=1
A0A167DA54_9ASCO68.37%1963e-97Ert1p OS=Sugiyamaella lignohabitans GN=ERT1 PE=4 SV=1
A0A1D8PSC7_CANAL41.63%4182e-93Zcf11p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ZCF11 PE=4 SV=1
A0A1E4TIS8_9ASCO64.86%1851e-88Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20152 PE=4 SV=1
ERT1_YEAST54.36%1951e-70Transcription activator of gluconeogenesis ERT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERT1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9279
Predicted cleavage: 59

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 673

Detailed signature matches

    1. SM00066 (gal4_2)
    2. SSF57701 (Zn2/Cys6 ...)
    3. PS50048 (ZN2_CY6_FU...)
    4. cd00067 (GAL4)
    1. cd00130 (PAS)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Residue annotation

  1. DNA binding site c...
  2. Zn2+ binding site ...
  3. putative active si...
  4. heme pocket cd00130

Protein sequence

>MCA_04873_1
MSSSSSSSSAKTPASKAQQNFTPISGKQVVANRAIANAEPNPPQVIISPRTGKPKRRKATRACIHCQRTHLTCDNNRPCE
QCVTRGLSETCRDGVRKKAKYLADVPDSVAMSEEALKFDPRYKKKNAKTQTAANRGKAASATTAANNTKKSAQNDMTSSL
MGKDTSISKPLVIPESVRNPSTLLAGNSATAVQSPSLLLNNFNNQSESGQLNLGNSSSIPPYNSLLPNLGPAGPAGAQSY
STSNVELSHKIQNQSQSVFKDKTSEKQQQQQQQQDLSGWDFDFRPSRHNFQSMAVNMEYSILSNILNTSMQPPYGIELPS
GSQPGYSPSLSSTGGDSPSLAKQNIPDLYGTPQSTAQTSVQNSSLVHLNSLNQYALGLSNNGIVQNLPEVLETVNKLKQA
QENSWIAGPDSPSGPKRPLSLTISVKPVTPHNTPTNPQNTPSNENSLDDSYNENSNTSYSSYFKQPYMNRMFDDGWLFRK
YSEPADIYASVKQPYSYTPAYHQLTIYIRTRFSREQQLKIAKCMASYRPSFIACTNTLKEDDLIFMEQCFQRTLLEYEKF
ISYSGTPTLIWRRTGQVAAVGKEFCILTGWPRERLLNEQTFVVELMDDNSVLEYFEMFSKMAFGDSIGATMTECTLLTPQ
GQKIKTSSIWTLKRDVFGIPMMIVGNFLPILNQ

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0008270 zinc ion binding

Cellular Component

GO:0005634 nucleus