Protein

MCA_04830_1

Length
461 amino acids

Gene name: ALG2

Description: Alpha-1,3/1,6-mannosyltransferase ALG2

Browser: contigC:4193924-4195408-

RNA-seq: read pairs 1450, FPKM 38.8, percentile rank 59.6% (100% = highest expression)

Protein function

Annotation:ALG2Alpha-1,3/1,6-mannosyltransferase ALG2
KEGG:K03843ALG2 alpha-1,3/alpha-1,6-mannosyltransferase [EC:2.4.1.132 2.4.1.257]
EGGNOG:0PFGAALG2Alpha-1,3-mannosyltransferase alg-2
SGD closest match:S000003033ALG2Alpha-1,3/1,6-mannosyltransferase ALG2
CGD closest match:CAL0000176395ALG2Alpha-1,3/1,6-mannosyltransferase ALG2

Protein alignments

%idAln lengthE-value
MIA_03688_164.06%4480.0MIA_03688_1
A0A0J9XLB6_GEOCN60.49%4480.0Similar to Saccharomyces cerevisiae YGL065C ALG2 Mannosyltransferase that catalyzes two consecutive steps in the N-linked glycosylation pathway OS=Geotrichum candidum GN=BN980_GECA32s00076g PE=4 SV=1
UniRef50_A0A0J9XLB660.49%4480.0Similar to Saccharomyces cerevisiae YGL065C ALG2 Mannosyltransferase that catalyzes two consecutive steps in the N-linked glycosylation pathway n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XLB6_GEOCN
A0A167FFL3_9ASCO51.86%4302e-147GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase OS=Sugiyamaella lignohabitans GN=ALG2 PE=4 SV=1
A0A060TBP7_BLAAD51.06%4238e-140ARAD1D36718p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D36718g PE=4 SV=1
A0A1E3PSU5_9ASCO48.28%4664e-137Putative asparagine-linked glycosylation protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49128 PE=4 SV=1
ALG2_YARLI45.00%4402e-120Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ALG2 PE=3 SV=1
A0A1E4TKC9_9ASCO45.75%4354e-117Glycosyltransferase family 4 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30449 PE=4 SV=1
ALG2_YEAST44.06%4381e-115Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ALG2 PE=1 SV=2
ALG2_CANAL44.04%4458e-115Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ALG2 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0020

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 461

Detailed signature matches

  1. Domain IPR028098
    Glycosyltransferase subfamily 4-like, N-terminal domain
    1. PF13439 (Glyco_tran...)
  2. Domain IPR001296
    Glycosyl transferase, family 1
    1. PF00534 (Glycos_tra...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.40.50...
  3. NON_CYTOPLASM... (N...)
  4. SSF53756 (UDP-Glyco...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. cd03805 (GT1_ALG2_like)

Residue annotation

  1. putative ADP-bindi...

Protein sequence

>MCA_04830_1
MSHLKIAFIHPDLGIGGAERLVVDAAVGLQELGHYVTIYTSHFDKKRAFPETTDGKLKIKVLGDGIVPRNFHGKFSIVCA
MLRQLHLIFALLNTKEGQAYDLFVVDQLSICIPFIREYAPNSRILFYGHFPDKLLADHESILKKIYRFPFDVLEQWSTSQ
SDVIIVNSKFTRSVFEKEFPKIQKELGVAYPCVNTKPTTYEHSPFAPYSFVLSINRFEKKKNVELAVNAFTLALKQAPPE
EAGKHKLILAGGYDPRVQENLEYMAQLQMLCKKNQLSYVVVWPTDGPSAYNTRDVQSKNVVFIPSVSHNIKQSLLADAAL
LAYTPSNEHFGIVPLEAMFAGTPVIATNTGGPLETITSETGWLLPPDADKWAEIFAYSLFSISPEERLRFQENGRKRVLE
NFSEIQMARQFEKYGQLAIATQRKKDFSLKLLEIVIISLMVILVFGTFTIYSRPRRSPNIA

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.