Protein
MCA_04758_1
Length
647 amino acids
Description: Rab5 GDP/GTP exchange factor, VPS9-like protein
Browser: contigC:3961624-3963638-
RNA-seq: read pairs 1745, FPKM 33.3, percentile rank 55.5% (100% = highest expression)
Protein function
| Annotation: | Rab5 GDP/GTP exchange factor, VPS9-like protein | ||
|---|---|---|---|
| KEGG: | K20131 | RABGEF1 | Rab5 GDP/GTP exchange factor |
| EGGNOG: | 0PIQF | PGUG_02060 | Guanine nucleotide exchange factor Vps9 |
| SGD closest match: | S000004563 | VPS9 | Vacuolar protein sorting-associated protein 9 |
| CGD closest match: | CAL0000186676 | orf19.5533 | Guanine nucleotide exchange factor |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03704_1 | 59.47% | 570 | 0.0 | MIA_03704_1 |
| A0A0J9XDD2_GEOCN | 61.82% | 495 | 0.0 | Similar to Saccharomyces cerevisiae YML097C VPS9 A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport OS=Geotrichum candidum GN=BN980_GECA10s02320g PE=4 SV=1 |
| A0A060T504_BLAAD | 57.82% | 486 | 0.0 | ARAD1C07546p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C07546g PE=4 SV=1 |
| UniRef50_A0A060T504 | 57.82% | 486 | 0.0 | ARAD1C07546p n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A060T504_BLAAD |
| A0A167D7Q7_9ASCO | 53.45% | 522 | 2e-173 | Guanine nucleotide exchange factor VPS9 OS=Sugiyamaella lignohabitans GN=VPS9 PE=4 SV=1 |
| Q6C3S0_YARLI | 49.42% | 518 | 2e-153 | YALI0E32593p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E32593g PE=4 SV=1 |
| A0A1E3PNR8_9ASCO | 47.27% | 495 | 3e-141 | Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_13253 PE=4 SV=1 |
| A0A1E4TAI8_9ASCO | 44.22% | 493 | 5e-126 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3386 PE=4 SV=1 |
| A0A1D8PPY0_CANAL | 44.44% | 279 | 4e-73 | Guanine nucleotide exchange factor OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5533 PE=4 SV=1 |
| VPS9_YEAST | 46.15% | 260 | 4e-70 | Vacuolar protein sorting-associated protein 9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS9 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0023
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
647
Detailed signature matches
-
-
SSF46934 (UBA-like)
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no IPR
Unintegrated signatures
-
-
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SSF109993 (VPS9 domain)
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cd14369 (CUE_VPS9_like)
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mobidb-lite (disord...)
Residue annotation
-
polypeptide substr...
Protein sequence
>MCA_04758_1 MSLLDHDDADIPTSQNDVQTPFTTALIPELATPATSGSSLKQDVSSLQPESKRTATTATPSESSSTIENTTTASSNPSPS SSAAMKGILDEFDPLATRNKSTPKPEESSSKNPEDLIPSEKQSTNVAEKKESSKAKTKSKSSSKPNDQQQDAPMNEKQPS SSSTPKDPSAPPPFDFQRFLDLLRHKSADPIARYLKSFLQEFNKRVWTADEQVKIITDFEHFIAGKMDQHPPFSTLSDAE MDNAMEGMEKLIMNRLYTKTFSPEIPPNKRTDSHEEDVIRDTVLDDKMSLWKWIEGRHLDIPNKFLRNGEAFVKLASDEL RKINHYRAPRDKVVCILNCCKVIFGLLRQSSSEENADGFLPILIYVVIKAHPKNMISNMNYIQRFRRPEKLNGEAGYYLS SLQGAVSFIETLDHQSLSISDEEFNKNMDAAISEQKKQKEQQEQERLAQESSQPPITPIRGLTPEPGARTGTGSPRTASG NLTPSAVLQSSAGLLAAPLKSISKLFDQTASNTRSNDSSNSGSPVISGQTRTFESQDYAARQEQLSSRKNNDKEDKELMD ALYKSLDNGNNANSNAPKLSPEELAARQISAEEEEARRISQQEFESVVETLSQMFPTLDRNVIVDVATEKQGRVGAAVDS CLALVST
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005515 protein binding
Cellular Component
None predicted.