Protein

MCA_04752_1

Length
357 amino acids

Gene name: RFC3

Description: Replication factor C subunit 3

Browser: contigC:3942989-3944243+

RNA-seq: read pairs 554, FPKM 19.1, percentile rank 40.3% (100% = highest expression)

Protein function

Annotation:RFC3Replication factor C subunit 3
KEGG:K10756RFC3_5 replication factor C subunit 3/5
EGGNOG:0PFQPPGUG_02820replication factor c
SGD closest match:S000005234RFC3Replication factor C subunit 3
CGD closest match:CAL0000191573RFC3Replication factor C subunit 3

Protein alignments

%idAln lengthE-value
MIA_05229_174.93%3350.0MIA_05229_1
A0A0J9XJU8_GEOCN67.34%3492e-176Similar to Saccharomyces cerevisiae YJR068W RFC2 Subunit of heteropentameric Replication factor C (RF-C) OS=Geotrichum candidum GN=BN980_GECA23s00318g PE=4 SV=1
A0A1E3PF00_9ASCO64.60%3391e-163Putative replication factor C (RF-C) subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84188 PE=4 SV=1
A0A060T3P6_BLAAD63.14%3312e-160ARAD1C38852p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38852g PE=4 SV=1
Q6CI37_YARLI62.61%3371e-152YALI0A02068p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A02068g PE=4 SV=1
UniRef50_Q6CI3762.61%3372e-149YALI0A02068p n=289 Tax=Fungi TaxID=4751 RepID=Q6CI37_YARLI
A0A1D8PNV1_CANAL59.88%3392e-151Replication factor C subunit 3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RFC3 PE=4 SV=1
RFC3_YEAST59.88%3293e-147Replication factor C subunit 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RFC3 PE=1 SV=1
A0A1E4TDN9_9ASCO59.64%3325e-145Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_97161 PE=4 SV=1
A0A167FC67_9ASCO50.00%1782e-52Replication factor C subunit 2 OS=Sugiyamaella lignohabitans GN=RFC2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0324

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 357

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  3. Domain IPR003959
    ATPase, AAA-type, core
    1. PF00004 (AAA)
  4. Domain IPR032423
    AAA C-terminal domain
    1. PF16193 (AAA_assoc_2)
  5. Domain IPR008921
    DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
    1. SSF48019 (post-AAA+...)
  6. Domain IPR013748
    Replication factor C, C-terminal
    1. PF08542 (Rep_fac_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.8.60
  2. G3DSA:1.20.27...
  3. G3DSA:3.40.50...
  4. cd00009 (AAA)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...
  4. arginine finger cd...

Protein sequence

>MCA_04752_1
MSTESKDKGKTKSTTSVTEEDLLPWVEKYRPSSLDEVAGQDHVVSTVRKFIEASRLPHLLFYGPPGTGKTTTILALAREL
YGEKSFRHMVLELNASDDRGIDVVRNQIKSFASTKQIFSTSKHDFKLVILDEADAMTNVAQNALRRVIEKYTVHTRFCII
ANYAHKLNPALLSRCTRFRFSPMAPEAIDKRLDVVIEQEKVKIDPDARKALVKLSKGDMRKALNVLQPCYLATKESVDGK
EEQQTITEEMIYECVGSPQPSDVRAIMESILQANWTTAVQAVDTIKKSKGLALADILDSLTEEFESYELKPEARIQLLEG
LSEVEYRLSSGGNEKIQTSAAIGVVKKAMDIQGGIKV

GO term prediction

Biological Process

GO:0006260 DNA replication

Molecular Function

GO:0003677 DNA binding
GO:0005524 ATP binding

Cellular Component

None predicted.