Protein
MCA_04732_1
Length
557 amino acids
Gene name: TCP1
Description: alpha subunit of chaperonin-containing T-complex
Browser: contigC:3866865-3868673+
RNA-seq: read pairs 7712, FPKM 170.8, percentile rank 86.3% (100% = highest expression)
Protein function
| Annotation: | TCP1 | alpha subunit of chaperonin-containing T-complex | |
|---|---|---|---|
| KEGG: | K09493 | CCT1 | T-complex protein 1 subunit alpha |
| EGGNOG: | 0PHQZ | FG05250.1 | t-complex protein 1 subunit alpha |
| SGD closest match: | S000002620 | TCP1 | T-complex protein 1 subunit alpha |
| CGD closest match: | CAL0000181702 | TCP1 | Chaperonin-containing T-complex alpha subunit |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03774_1 | 91.38% | 557 | 0.0 | MIA_03774_1 |
| A0A0J9XDM3_GEOCN | 89.59% | 557 | 0.0 | Similar to Saccharomyces cerevisiae YDR212W TCP1 Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol OS=Geotrichum candidum GN=BN980_GECA11s01489g PE=3 SV=1 |
| A0A060T802_BLAAD | 83.48% | 557 | 0.0 | ARAD1C32318p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32318g PE=3 SV=1 |
| Q6CEG7_YARLI | 83.33% | 558 | 0.0 | YALI0B15774p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15774g PE=3 SV=2 |
| A0A1E3PS80_9ASCO | 83.24% | 549 | 0.0 | Alpha subunit of chaperonin-containing T-complex OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44536 PE=3 SV=1 |
| TCPA_YEAST | 81.04% | 559 | 0.0 | T-complex protein 1 subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TCP1 PE=1 SV=2 |
| UniRef50_P12612 | 81.04% | 559 | 0.0 | T-complex protein 1 subunit alpha n=737 Tax=Eukaryota TaxID=2759 RepID=TCPA_YEAST |
| A0A161HKB4_9ASCO | 85.97% | 506 | 0.0 | Chaperonin-containing T-complex alpha subunit TCP1 OS=Sugiyamaella lignohabitans GN=TCP1 PE=3 SV=1 |
| Q59QB7_CANAL | 78.16% | 554 | 0.0 | Chaperonin-containing T-complex alpha subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TCP1 PE=3 SV=1 |
| A0A1E4TBZ1_9ASCO | 76.40% | 555 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32571 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1919
Predicted cleavage: 11
Protein family membership
- Chaperonin Cpn60/TCP-1 family (IPR002423)
- Chaperone tailless complex polypeptide 1 (TCP-1) (IPR017998)
- T-complex protein 1, alpha subunit (IPR012715)
- Chaperone tailless complex polypeptide 1 (TCP-1) (IPR017998)
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
557
Detailed signature matches
no IPR
Residue annotation
-
ring oligomerisati...
-
ATP/Mg binding sit...
-
stacking interacti...
Protein sequence
>MCA_04732_1 MSTVFSSARSETLFLNGEKISGDDIRNQNVLACQAIANVLKSSLGPVGLDKMLVDDIGDVTVTNDGATILNLLDVEHPAG KILVELAQQQDREVGDGTTSVVIIASELLKRANELVKNKIHPTTIITGYRLALREATKFINDTMSMSVESLGKETLVNIA KTSMSSKIIGPDSEFFSQMVVDAMIAVKTTNTRGDTKYPVKAVNVLKAHGKSALESILVKGYALNCTVASQAMKKRITGA KIAVLDMNLQKARMPMGVNITIDDPEQLEAIRKREFDIIVERINKIIDAGANVVLTTKGIDDLCLKLFVEAGVMAVRRCK KEDLRRIARATGATMISTLSNLDGEEVFESSYLGQAEEVAQERVSDDELILVKGTKVHSSSSIILRGSNDYQLDEMERSI HDSLSVVKRTLESGYVVPGGGAVEAALNIYLENFATSVGSREQLAIAEFANALLIIPKTLAVNAAKDSSELVAKLRAYHA ASQSVSLTDVKKRNYKNYGLDLIKGKVIDEVKAGVLEPTISKIKSLKSALEACVAILRIDTMIRVEPEQQQEDPHDH
GO term prediction
Biological Process
GO:0006457 protein folding
Molecular Function
GO:0005524 ATP binding
GO:0051082 unfolded protein binding
Cellular Component
None predicted.