Protein
MCA_04694_2
Length
608 amino acids
Gene name: ALG3
Description: Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase
Browser: contigC:3745862-3747760-
RNA-seq: read pairs 1036, FPKM 21.0, percentile rank 42.7% (100% = highest expression)
Protein function
| Annotation: | ALG3 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase | |
|---|---|---|---|
| KEGG: | K03845 | ALG3 | alpha-1,3-mannosyltransferase [EC:2.4.1.258] |
| EGGNOG: | 0PJ0Q | ALG3 | Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol (By similarity) |
| SGD closest match: | S000000178 | ALG3 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase |
| CGD closest match: | CAL0000175383 | orf19.1092 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01830_1 | 50.72% | 276 | 7e-72 | MIA_01830_1 |
| A0A0J9XH98_GEOCN | 50.45% | 224 | 8e-53 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Geotrichum candidum GN=BN980_GECA16s02122g PE=4 SV=1 |
| UniRef50_A0A0J9XH98 | 50.45% | 224 | 2e-49 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XH98_GEOCN |
| A0A060T7C8_BLAAD | 44.30% | 237 | 8e-47 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D02244g PE=4 SV=1 |
| A0A1E3PPT8_9ASCO | 42.41% | 224 | 4e-41 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46203 PE=4 SV=1 |
| A0A1E4TC03_9ASCO | 38.67% | 225 | 5e-38 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_45736 PE=4 SV=1 |
| Q6C774_YARLI | 39.91% | 223 | 1e-37 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E03190g PE=4 SV=1 |
| ALG3_YEAST | 40.88% | 159 | 1e-28 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ALG3 PE=1 SV=1 |
| A0A1D8PQE0_CANAL | 36.86% | 255 | 7e-22 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1092 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0080
Protein family membership
- Glycosyltransferase, ALG3 (IPR007873)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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-
TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_04694_2 MGSVKSESSFSLSKFGYYPFGLLLLIAELGLGYLIINKIPYTEIDWTAYMQQVSQIVERSERNYTLIEGGTGPLVYPGGH VAIYSILWALTNKGQEIQLAQYMFLLLYILTLAIVIICVYRNTELQLGPQETLSAEEAYDKSRSTKSSKSSSFVASIPPY IWTLPLLCLSKRLHSIYMLRLFNDCFGTLFSVIFVWIMANNRWVLSSIVLSVAVSIKMNSLLYIPGAAVIYLQAVGLKKS ITRIAFPFILVQIIMALPFILDLTPLTQLVSEKLDLLPFQESSNSTYPELTHTTLQMSPEGVLESLKIIASNISKSSSYV YKDVSQYLSAYFSIPLAQILRVIVKDIKFSPYALDYVKQAFDFSRVFMYKWTVNWRFIPEDIFVSPVFGKILLGLQLIVT LVGFATHKSGWWFSPLKPLPIGSQYVANGSSTGASTSIAVKQRQNTMRKVTPISVVKSPSDFTFISLVRTLFLDNTTDYV RQKRIKEGMNKDYVLKTLISSNLIGILFARSLHYQFYSWFYWSVPYALYVCSKNFSKDQKPSFLGVLFSLGIWLAQEVAW HTYPSTNLSSLIVNVSLVYMVFGLWYNGYRSYTLLKKEVLANDIQKVK
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0016758 transferase activity, transferring hexosyl groups
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane