Protein

MCA_04671_1

Length
734 amino acids

Gene name: YPK1

Description: Serine/threonine protein kinase Ypk1

Browser: contigC:3653805-3656246-

RNA-seq: read pairs 4434, FPKM 74.5, percentile rank 73.9% (100% = highest expression)

Protein function

Annotation:YPK1Serine/threonine protein kinase Ypk1
KEGG:K13303SGK2 serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
EGGNOG:0PGHPFG05845.1serine threonine protein kinase
SGD closest match:S000001609YPK1Serine/threonine-protein kinase YPK1
CGD closest match:CAL0000177447orf19.399Serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
A0A0J9XIB2_GEOCN71.35%5760.0Similar to Saccharomyces cerevisiae YKL126W YPK1 Serine/threonine protein kinase that phosphorylates and downregulates flippase activator Fpk1p OS=Geotrichum candidum GN=BN980_GECA18s01726g PE=4 SV=1
A0A167E8K8_9ASCO64.86%5890.0Serine/threonine protein kinase YPK1 OS=Sugiyamaella lignohabitans GN=YPK1 PE=4 SV=1
MIA_00118_188.92%3880.0MIA_00118_1
A0A060T7D3_BLAAD64.58%5900.0ARAD1B22858p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B22858g PE=4 SV=1
A0A1E3PJ30_9ASCO60.98%5740.0Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83321 PE=4 SV=1
Q6C6T3_YARLI78.57%3780.0YALI0E06501p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E06501g PE=4 SV=1
UniRef50_U9UPL356.37%5730.0Uncharacterized protein n=8 Tax=Fungi TaxID=4751 RepID=U9UPL3_RHIID
A0A1E4TJS7_9ASCO61.49%4830.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30275 PE=4 SV=1
YPK1_YEAST72.32%3540.0Serine/threonine-protein kinase YPK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPK1 PE=1 SV=2
Q59QB9_CANAL70.17%3522e-168Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.399 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2466

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 734

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. Domain IPR000961
    AGC-kinase, C-terminal
    1. SM00133 (pkinase_C_6)
    2. PS51285 (AGC_KINASE...)
  4. Domain IPR017892
    Protein kinase, C-terminal
    1. PF00433 (Pkinase_C)
  5. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  6. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.51...
  2. G3DSA:3.30.20...
  3. cd11651 (YPK1_N_like)
  4. mobidb-lite (disord...)

Protein sequence

>MCA_04671_1
MSTWKLTKKFKETHLSKSPFSTSKQQQQQQNQSEDSDSEHSSSQRSTFNLPSVTASQRKNTPPSSSSPSKSSSSSTPTKQ
SSIDSSAYSNLSPSKNSSSSNLELDSPSKTKMAFSKLSPNNNIKYDSSNTQQSIPQSSSSSSSSSTTNRHQRTSSTSIKP
GLLVVSISGATGLSLPPGYVSNPFIQNYMARMSPTKSSSILRTPMIPSSLSGASASSSSYIARNENTSLATGASTATPVN
RKRMPVFLVIEFDKTQVVLEATGGPLEAPTWETTSNFDVSRVETLNFQIYTRIPNISASSPSNSTTASSIPSAASLNGSA
NSSSSNAAPVSPFASTANGAPGSSVAPARKYEEIFLGACKVAVDPSQLSNSPGNLFDGSIPLSGGSGKLHLRIDYRPNLQ
KKPLTIDDFDLLKVVGKGSFGKVMQVRKRDTQRIYALKTIRKAHIVSRSEVNHTLAERTVLAQIDNPFIVPLKFSFQSPE
KLYLVLAFVNGGELFHHLQREGKFDLNRSRFYTAELLCALECLHEYNVIYRDLKPENILLDYTGHIALCDFGLCKLNMKG
QEKTNTFCGTPEYLAPELLLAQGYTKVVDWWTLGVLFYEMLTGLPPFYDENVNEMYRKILQDPLRFPEDMDREAKSLIQG
LLERNPEKRLGVNGAAEIKAHPFFAQIDWRRLMAKKYAAPFKPAVESATDTSNFDQEFTSEVPADSVVNGDYLSESVQKQ
FGGWSYSADSKLAF

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.