Protein

MCA_04653_1

Length
985 amino acids

Gene name: PFK2

Description: ATP-dependent 6-phosphofructokinase subunit beta

Browser: contigC:3610074-3613032+

RNA-seq: read pairs 19642, FPKM 246.1, percentile rank 90.3% (100% = highest expression)

Protein function

Annotation:PFK2ATP-dependent 6-phosphofructokinase subunit beta
KEGG:K00850pfkA 6-phosphofructokinase 1 [EC:2.7.1.11]
EGGNOG:0PI6NPFK2phosphohexokinase
SGD closest match:S000004818PFK2ATP-dependent 6-phosphofructokinase subunit beta
CGD closest match:CAL0000190617PFK2ATP-dependent 6-phosphofructokinase

Protein alignments

%idAln lengthE-value
MIA_03927_179.66%9880.0MIA_03927_1
A0A0J9X4P4_GEOCN68.51%9940.0ATP-dependent 6-phosphofructokinase OS=Geotrichum candidum GN=BN980_GECA02s05433g PE=3 SV=1
A0A167DNJ0_9ASCO62.91%9760.0ATP-dependent 6-phosphofructokinase OS=Sugiyamaella lignohabitans GN=PFK2 PE=3 SV=1
A0A1E3PPM6_9ASCO60.95%9860.0ATP-dependent 6-phosphofructokinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46161 PE=3 SV=1
A0A060TAE5_BLAAD61.79%9840.0ATP-dependent 6-phosphofructokinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D26422g PE=3 SV=1
A0A1E4TKB2_9ASCO57.74%9820.0ATP-dependent 6-phosphofructokinase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_83583 PE=3 SV=1
PFKA_YARLI55.23%9760.0ATP-dependent 6-phosphofructokinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PFK1 PE=2 SV=2
Q5AGZ8_CANAL53.64%9900.0ATP-dependent 6-phosphofructokinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PFK2 PE=3 SV=1
UniRef50_A0A1V2LME154.61%9540.0ATP-dependent 6-phosphofructokinase n=3 Tax=Pichia kudriavzevii TaxID=4909 RepID=A0A1V2LME1_PICKU
PFKA2_YEAST52.26%9950.0ATP-dependent 6-phosphofructokinase subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PFK2 PE=1 SV=4

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1239

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 985

Detailed signature matches

  1. Family IPR022953
    ATP-dependent 6-phosphofructokinase
    1. PR00476 (PHFRCTKINASE)
  2. Family IPR009161
    ATP-dependent 6-phosphofructokinase, eukaryotic-type
    1. PIRSF000533 (ATP_PF...)
    2. TIGR02478
    3. MF_03184 (Phosphofr...)
  3. Domain IPR000023
    Phosphofructokinase domain
    1. PF00365 (PFK)
    2. SSF53784 (Phosphofr...)
  4. SITE IPR015912
    Phosphofructokinase, conserved site
    1. PS00433 (PHOSPHOFRU...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. G3DSA:3.40.50...

Protein sequence

>MCA_04653_1
MPNYPKLLKGISSLSICTSDENTYRKTIAFYEQFGFINVHNYSNTDSDSLVEKSLHAAHSNDSRKEAWLNLLPEVDYGHT
DASPDSGTTLKIRLTNHGPTAEECQKKAKNFLEGPDQDIDWRAVACLFIFSTQDMDNVLSILDSYPIISGVKSYIQFRPN
EVSPIEVYGIDPCGNVIGFTLRPNPFSVVDPGYVSSRANDPYGSGSVSGFATPKGKSGKGGQFDLSDAFSRRRIGIMTSG
GDAPGMNACVRAVVRTAIHRGCDVFAIYEGYDGLVKGGNLIKQMSWDDVRGWLAIGGTNIGTARCAEFRERPGRLAGAKN
MVKNGIDGLIVCGGDGSLTGADTFRAEWPSLLEELVKKGEITQEEKEAHEHLYICGLVGSIDNDMASTDVTIGAFSSLQR
ICQSVDYIDATAQSHSRAFVIEVMGRHCGWLALMAGIATGADFVFLPERPPSPDEWKNNMCKVVKRHREFGKRKTIVIVA
EGAIDSELNPIHCDDVKKVLVDLGLDTRVTTLGHVQRGGNAVAFDRLLATLQGVDAVDAILSATPDSPSPMIGITENKIV
RRDLMESVALTKSVADAIKVKDFDKAMSLRNTEFGENWENFMTINSADKLSPKNPAEKPLNIAVINVGAPAGGMNTAIRA
MAGYCYSRGHKPYAIHNGFTGLARHESVRELDWLEVEEWVMRGGSEIGTNRSLPDTDIGMIAYYFQKYKFDGLIIIGGYE
AYHSLHQLQQSRTAYPAFRIPMVCIPATISNNVPGTEYSLGSDTCLNALVDYCDIIKQSASASRRRVFVVEVQGGNSGFV
ASYAGLVTGAHATYLPEDGISLRQLESDIEYIKESFEHDQGKNRAGKLILRNEKSSNTFSTEIIVNIIKDESNGRFEART
AIPGHVQQGGNPSPLDRVRATRFAIQSCQFIESHQNTRDLAVDRQSKTAVVVGIRSSKLVFSNICQLWDFETEHSERRPK
KNIWAHMAQVADTLVGRPKVGKPFR

GO term prediction

Biological Process

GO:0006002 fructose 6-phosphate metabolic process
GO:0006096 glycolytic process

Molecular Function

GO:0003872 6-phosphofructokinase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm