Protein
MCA_04650_1
Length
343 amino acids
Gene name: HEM13
Description: Oxygen-dependent coproporphyrinogen-III oxidase
Browser: contigC:3601368-3602400+
RNA-seq: read pairs 5764, FPKM 207.0, percentile rank 88.5% (100% = highest expression)
Protein function
Annotation: | HEM13 | Oxygen-dependent coproporphyrinogen-III oxidase | |
---|---|---|---|
KEGG: | K00228 | CPOX | coproporphyrinogen III oxidase [EC:1.3.3.3] |
EGGNOG: | 0PIF2 | HEM13 | coproporphyrinogen III oxidase |
SGD closest match: | S000002451 | HEM13 | Oxygen-dependent coproporphyrinogen-III oxidase |
CGD closest match: | CAL0000191428 | HEM13 | Coproporphyrinogen oxidase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_04875_1 | 62.97% | 343 | 3e-150 | MIA_04875_1 |
A0A0J9X6L1_GEOCN | 60.35% | 343 | 9e-137 | Similar to Saccharomyces cerevisiae YDR044W HEM13 Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway OS=Geotrichum candidum GN=BN980_GECA04s04058g PE=4 SV=1 |
A0A060TJ26_BLAAD | 54.60% | 337 | 7e-115 | ARAD1D43406p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D43406g PE=4 SV=1 |
A0A167EGV1_9ASCO | 51.91% | 341 | 5e-112 | Coproporphyrinogen oxidase OS=Sugiyamaella lignohabitans GN=HEM13 PE=4 SV=1 |
UniRef50_K0KQ76 | 51.17% | 342 | 2e-105 | Coproporphyrinogen III oxidase, aerobic n=17 Tax=Opisthokonta TaxID=33154 RepID=K0KQ76_WICCF |
HEM6_YEAST | 50.88% | 340 | 4e-105 | Oxygen-dependent coproporphyrinogen-III oxidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HEM13 PE=1 SV=2 |
Q59MR4_CANAL | 51.18% | 340 | 2e-104 | Coproporphyrinogen oxidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HEM13 PE=4 SV=1 |
A0A1E3PDC4_9ASCO | 48.83% | 342 | 1e-100 | Coproporphyrinogen oxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28891 PE=4 SV=1 |
Q6C438_YARLI | 51.61% | 341 | 1e-98 | YALI0E29975p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E29975g PE=4 SV=1 |
A0A1E4TJ60_9ASCO | 42.17% | 351 | 3e-84 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30139 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.3549
Protein family membership
- Coproporphyrinogen III oxidase, aerobic (IPR001260)
Domains and repeats
None predicted.
Detailed signature matches
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PR00073 (COPRGNOXDASE)
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PIRSF000166 (Coprop...)
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SSF102886 (Copropor...)
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PF01218 (Coprogen_o...)
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PS01021 (COPROGEN_O...)
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Protein sequence
>MCA_04650_1 MASVRERMQKLIKDKQAEIVKVLESVEEEFSTTTPAKFFLDKWDRDDPKEGGGISAVIQGGDVIEKGGAMLSIVSSKLPP AGVQRMRADHKALDILAEKQANVSNPVSLPFDVCGLSLIMHPKNPYAPTVHLNYRYFEIRDPDDDSKVITWWFGGGADLT PHYLYEEDAQDFHAALKNACDTKLKSKKYYPKFKKWCDEYFYVKHRKENRGVGGIFFDDFGDASEDATDDEGNQLTQDDY LAFVEACLDAYISSYPKILRRRCQTPYTEKEVKWQHIRRGRYVEFNLIYDRGTQFGLATPNARIESILVSLPLHSSWEYM HAPEKGSHEEKTLEVLKHPKDWL
GO term prediction
Biological Process
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0004109 coproporphyrinogen oxidase activity
Cellular Component
None predicted.