Protein
MCA_04645_1
Length
1,163 amino acids
Gene name: KIN4
Description: Serine/threonine protein kinase; in S. cerevisiae it inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck
Browser: contigC:3585945-3589437-
RNA-seq: read pairs 1805, FPKM 19.2, percentile rank 40.3% (100% = highest expression)
Protein function
| Annotation: | KIN4 | Serine/threonine protein kinase; in S. cerevisiae it inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck | |
|---|---|---|---|
| EGGNOG: | 0PHT0 | FG00699.1 | serine threonine protein kinase |
| SGD closest match: | S000005759 | KIN4 | Serine/threonine-protein kinase KIN4 |
| CGD closest match: | CAL0000189750 | CAALFM_CR02210WA | Protein kinase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XCM6_GEOCN | 62.72% | 574 | 0.0 | Similar to Saccharomyces cerevisiae YOR233W KIN4 Serine/threonine protein kinase OS=Geotrichum candidum GN=BN980_GECA09s02540g PE=4 SV=1 |
| UniRef50_A0A0J9XIU8 | 88.27% | 324 | 0.0 | Similar to Saccharomyces cerevisiae YOR233W KIN4 Serine/threonine protein kinase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XIU8_GEOCN |
| A0A060T2H0_BLAAD | 61.12% | 517 | 0.0 | ARAD1C25212p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C25212g PE=4 SV=1 |
| Q6CB57_YARLI | 82.88% | 292 | 1e-166 | YALI0C21758p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C21758g PE=4 SV=1 |
| A0A1E3PH60_9ASCO | 80.00% | 305 | 4e-163 | Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47325 PE=4 SV=1 |
| Q59UZ0_CANAL | 68.83% | 308 | 3e-138 | Protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR02210WA PE=4 SV=1 |
| A0A1E4TH76_9ASCO | 68.58% | 296 | 6e-132 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26560 PE=4 SV=1 |
| KIN4_YEAST | 62.38% | 319 | 4e-125 | Serine/threonine-protein kinase KIN4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KIN4 PE=1 SV=1 |
| A0A167CKS8_9ASCO | 42.34% | 274 | 6e-57 | Non-specific serine/threonine protein kinase OS=Sugiyamaella lignohabitans GN=SNF1 PE=4 SV=1 |
| MIA_01361_1 | 42.55% | 275 | 1e-55 | MIA_01361_1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.7854
Predicted cleavage: 11
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
200
400
600
800
1000
1163
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_04645_1 MADPTIPPRVSSRLSNSAKLSNSISKRVHRESRFGDYLLGSTLGQGEFGKVKLGWRKDGKQPEQVAIKLIRKDTVPPKSN RETKVFREINALKILTHPNIVRLEEVIQNDKYIGIVLEYASGGELFDHILQHRYLKDNVACRLFAQLVSGVHYLHSKGIV HRDLKLENLLLDKHKNIMISDFGFANSFGCSPDGTINDLMATSCGSPCYAAPELVVSDAKYIGRKVDVWSCGVILYAMLA GYLPFDDDPDNPDGDDITQLYKYITTTPLTFPEYVQAMPRDLLRKILVSDPTQRISLNDIRSHAWLAPHAHFLSVTPEEW DRSFIHQSQIQQYLSTGANTKNSNTTAIKNGYLPTSHSHTAFTTPPLSSAAPNAVGSNPPEQAIPSLPNLPQSAGNKNVS STLVTPSAQKGNGAAAAPFVLPSQPWSNSGSDNNNNTQGTIGNLTPASSAFPSHAQEHTRPTSMFVPATSSSYHTRHNSA QIDSTPSLSSTPPPTTQSYNTHSRRHSVQTGFTKPVTHQRFSTTTGYNSTTPSSLRNSLDIPRTTPEVSQQQRRPLSVAS TNSSNDEVLASLDISNPNNSSVAVASTPNSSSTNATLVTNTTTPPGVNSSSSNNGSPTKAVHTLYNSSSLSSSNRNLITT IDESDATQSFGIPLSTSPTPDSKIADPVSTLSESLSKSSVSKPSGASRLPPASRKPRPTSYQPYGHSYPSSLNAFITPPL EKFPNEKNMNFQTPTQSEPRVGITQDTALPGEISRPAFKGSATSNSLVGMVNTNNNQSNTSTTPSSPQNELYNGLNDNVP QPFANQGSVKSTQSSQTTRVASDSANEASTLGSHTASALHEKSKIGTDQRLPSFDFPNRTNGSENTSVDVIPNNINHNTS NLSVNTSTSNPHSNDTAGTHTPIYNPVYLSYPKKSHKKASSSISYGADRFFSRLMGNGNEALVDSSSIASSNTNSNTTVY GAQLNVPVQNLEQQQPQQNYRQHRYTKSVATPQSNINNPSTPSSYNFRFSSDESNNNNNNNNSISSSKTTPKHKRFSFMS LYSFGSGNEKAKSNYTPPITITSSDRKVLEPASPNIQRRTNSHMRHASVANDRPSSYYHTSSGNTINLKNSEMGFFHQNN SGFMVQNIPEFPSDGGNGNGKKDQSSAARKVMDFFKRRSRIVT
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Cellular Component
None predicted.