Protein
MCA_04626_1
Length
512 amino acids
Gene name: AFG1A
Description: Protein AFG1; may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane
Browser: contigC:3543595-3545431+
RNA-seq: read pairs 1502, FPKM 36.2, percentile rank 58.0% (100% = highest expression)
Protein function
| Annotation: | AFG1A | Protein AFG1; may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane | |
|---|---|---|---|
| KEGG: | K18798 | AFG1 | peroxisome-assembly ATPase [EC:3.6.4.7] |
| EGGNOG: | 0PFGJ | FG09624.1 | mitochondrial ATPase |
| SGD closest match: | S000000778 | AFG1 | Protein AFG1 |
| CGD closest match: | CAL0000198513 | orf19.2891 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04350_1 | 68.19% | 503 | 0.0 | MIA_04350_1 |
| A0A0J9X7F6_GEOCN | 58.70% | 506 | 0.0 | Similar to Saccharomyces cerevisiae YEL052W AFG1 Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits OS=Geotrichum candidum GN=BN980_GECA04s04795g PE=4 SV=1 |
| A0A060T7W9_BLAAD | 57.48% | 461 | 3e-178 | ARAD1C31394p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C31394g PE=4 SV=1 |
| A0A1E3PEC3_9ASCO | 55.22% | 469 | 7e-173 | AFG1-like ATPase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84354 PE=4 SV=1 |
| UniRef50_A0A1E3PEC3 | 55.22% | 469 | 2e-169 | AFG1-like ATPase n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3PEC3_9ASCO |
| A0A167EM36_9ASCO | 54.61% | 445 | 6e-165 | Afg1p OS=Sugiyamaella lignohabitans GN=AFG1 PE=4 SV=1 |
| Q6CAR2_YARLI | 48.09% | 472 | 6e-144 | YALI0D00649p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D00649g PE=4 SV=1 |
| A0A1E4TGZ8_9ASCO | 46.52% | 460 | 1e-133 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2747 PE=4 SV=1 |
| AFG1_YEAST | 44.49% | 490 | 3e-132 | Protein AFG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AFG1 PE=1 SV=1 |
| A0A1D8PML6_CANAL | 43.84% | 511 | 5e-125 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2891 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9301
Predicted cleavage: 25
Protein family membership
- ATPase, AFG1-like (IPR005654)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
450
512
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
cd00009 (AAA)
-
mobidb-lite (disord...)
Residue annotation
-
Walker A motif cd0...
-
ATP binding site c...
-
Walker B motif cd0...
Protein sequence
>MCA_04626_1 MSLRTLSIFRSVISISHLKNIRPYSTNQPITTTASNESIVNDDDIVRNPVEQYDHLVQINKIRNDPYQRKMLSNLSFLHA ELLNYTPPNISDISATPSSNSILGKVFSIFKKPSSSSSSSLSSFDGPSNLPIGSQPKGIYLYGDVGSGKTMLMDMFYTTV PKHLTKRRIHFHAFMQDVHKRNHKLHEKYGLDYDTAPTIATEIAKEANVLCFDEFQVTDVADAMILRRLYENFLSPRLGV VIFMTSNRAPEELYKDGIQRSSFIPTIELIKLKSHVMFLDSPTDYRKIDRPSQGTYFSPPLPTQTLADVKEQAQQHVDKW FEYFSQGMTQFVEYNVALTIWGRPVIIPKCIVGAVAQFTFNELCNQPLSAADYLEITSQFPQIIITDIPLLSIKQKDVTR RFITFLDAAYESHSKIAVTSEKPFDQLFTDEIPTYGKKSKVVLEFEEKQKKLNEQQNKKEEDKSSQLLEKDDDILSNSNM FSGEEERFAFARALSRLKQMASKEWHDYQVPK
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005524 ATP binding
Cellular Component
None predicted.