Protein

MCA_04624_1

Length
292 amino acids


Gene name: EHD3B

Description: 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

Browser: contigC:3536916-3537907+

RNA-seq: read pairs 6202, FPKM 261.5, percentile rank 90.8% (100% = highest expression)

Protein function

Annotation:EHD3B3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
KEGG:K07511ECHS1 enoyl-CoA hydratase [EC:4.2.1.17]
EGGNOG:0PHEJEnoyl-CoA hydratase
SGD closest match:S000002443EHD33-hydroxyisobutyryl-CoA hydrolase, mitochondrial
CGD closest match:CAL0000174772EHD33-hydroxyisobutyryl-CoA hydrolase, mitochondrial

Protein alignments

%idAln lengthE-value
MIA_01942_182.06%2624e-164MIA_01942_1
A0A167DDA2_9ASCO72.07%2906e-154Ehd3p OS=Sugiyamaella lignohabitans GN=EHD3 PE=3 SV=1
A0A0J9YHE2_GEOCN74.62%2602e-142Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA01s03046g PE=3 SV=1
A0A060T0U5_BLAAD72.90%2623e-140ARAD1C15686p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C15686g PE=3 SV=1
A0A1E4TAR7_9ASCO68.11%2549e-128Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_128769 PE=3 SV=1
UniRef50_A0A0E9NM4058.82%2891e-1101-acyl-sn-glycerol-3-phosphate acyltransferase n=2 Tax=Saitoella complicata NRRL Y-17804 TaxID=698492 RepID=A0A0E9NM40_9ASCO
A0A1E3PDQ1_9ASCO63.81%2572e-117ClpP/crotonase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84168 PE=3 SV=1
Q6CF43_YARLI57.84%2877e-114YALI0B10406p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10406g PE=3 SV=1
Q5AI24_CANAL29.74%1958e-163-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EHD3 PE=3 SV=1
HIBCH_YEAST28.43%1971e-143-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EHD3 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9907
Predicted cleavage: 58

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 292

Detailed signature matches

    1. PF00378 (ECH_1)
    1. SSF52096 (ClpP/crot...)
    1. PS00166 (ENOYL_COA_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd06558 (crotonase-...)

Residue annotation

  1. substrate binding ...
  2. oxyanion hole (OAH...
  3. trimer interface c...

Protein sequence

>MCA_04624_1
MITPSLFTRRILTANTTILRSTLFNIQKMSYSTGGSYEYILVSKPASGVRLIQLNRPKALNALFTPLIKELNQALREADA
EEDVGAVVITGNERAFAAGADIKEMKDLTVADAYGKDFIKSWSELMDISKPIIAAVNGYALGGGCELAMMCDMIYAGEKA
VFGQPEIKLGVLPGAGGTQRLVKLIGKSRAMEIILTGRNIPAAKALEWGMVANVFKPEELVDEAVKTAAEIASFSPLAVK
ACKEAVNESFNLPLEQGLKYERRLFHGIFGTQDQKEGMSAFAEKRKPNWTGK

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.