Protein
MCA_04620_1
Length
605 amino acids
Gene name: TRM6
Description: tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6
Browser: contigC:3527573-3529391+
RNA-seq: read pairs 1167, FPKM 23.8, percentile rank 46.1% (100% = highest expression)
Protein function
| Annotation: | TRM6 | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 | |
|---|---|---|---|
| KEGG: | K03256 | TRM6 | tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit |
| EGGNOG: | 0PJ0M | TRM6 | Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Binds RNA |
| SGD closest match: | S000005006 | GCD10 | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 |
| CGD closest match: | CAL0000185106 | TRM6 | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01938_1 | 59.82% | 565 | 0.0 | MIA_01938_1 |
| A0A0J9X2K5_GEOCN | 50.48% | 315 | 2e-91 | Similar to Saccharomyces cerevisiae YNL062C GCD10 Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p OS=Geotrichum candidum GN=BN980_GECA01s03090g PE=4 SV=1 |
| UniRef50_A0A0J9X2K5 | 50.48% | 315 | 5e-88 | Similar to Saccharomyces cerevisiae YNL062C GCD10 Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X2K5_GEOCN |
| A0A167E8Q1_9ASCO | 46.47% | 312 | 2e-81 | Gcd10p OS=Sugiyamaella lignohabitans GN=GCD10 PE=4 SV=1 |
| A0A060T905_BLAAD | 45.86% | 314 | 2e-78 | ARAD1C33902p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C33902g PE=4 SV=1 |
| TRM6_YARLI | 44.98% | 309 | 5e-77 | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=TRM6 PE=3 SV=1 |
| A0A1E3PTR6_9ASCO | 41.34% | 329 | 6e-66 | Gcd10p-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_76551 PE=4 SV=1 |
| A0A1E4TAR6_9ASCO | 37.86% | 309 | 2e-57 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_128801 PE=4 SV=1 |
| TRM6_CANAL | 37.42% | 318 | 4e-55 | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TRM6 PE=3 SV=1 |
| TRM6_YEAST | 37.97% | 316 | 6e-52 | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GCD10 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0392
Protein family membership
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_04620_1 MTDIKTTRHEKQLQVAAAVEQQEALDRTSVSNKKLNFNPLLRPEERDPDFNPFNQTFIKPNTFVLIRLPSENFRVVKMTP TASINLGKFGSFRVHDILGHPFGYTYEIFGIGPEEKGLTKNQKVKKGLKKLTKEEKRKLYEQQKQLQGEDEQAETVPPPG PQLRIVQGLDTMEEGGASTKDELDPDENNKDLMYDPQAMKLTMAEIEALKRSSVDAGREVISSMIKAHSSFDKKTTFSQE KYVKRKEQKFLRRFAPEPINSAEILNLYLEKDPHKVLDMSEESLGLLLSLGNVKPGGTYLVAEDTSGLLVAALLERMAGQ GTIVVAHANEHTRMDALKYLSVSDAWIESKVKTINWLDFLHPEEHDTGLESEGEDEDEEEQQQKGGGNNNVDEGTDIKSS INNTEPTTTTKSSSADSSYFLYKFVEKTPQEIASMKPHQRGQYYRRKKRYDEFIEVRALIDSQAFDAAFLATELDLPTLA PRVVDSLKGSAPLVIYSQFKENLVATSHVLQKDLRVLAPTLLETKVRKYQTLPGRMHPVMTMRGGGGYLLWGTRVIPTQV DAIGGSRGKKRKAVESPSTTSQPKSNTSNDIKDEPSSKQIKVDKD
GO term prediction
Biological Process
GO:0030488 tRNA methylation
Molecular Function
None predicted.
Cellular Component
GO:0031515 tRNA (m1A) methyltransferase complex